Overview The English-language Master's degree program in Molecular Biotechnology is unique in Austria: the emphases of the Master´s degree program are molecular medicine, human genetics, drug discovery and immunology. You will investigate the causes of diseases at the cellular level and learn how to develop new treatments and therapies for them. You will learn about the hot topics of big data, personalized data analysis and data security. The degree program is part of a large national and international network at university level.Contact usContact us!Elisabeth HablasVictoria Buchsbaum, MAVienna BioCenterHelmut-Qualtinger-Gasse 2, OG.A.011030 WienT: +43 1 606 68 77-3500 F: +43 1 606 68 77-3509biotechnologie@fh-campuswien.ac.atMap Vienna BioCenter (Google Maps)Office hours Mon to Fri, 8.00 a.m.-12.00 p.m. Information: Application and Admissionbiotechnologie@fh-campuswien.ac.atDuration of course4 SemestersOrganisational formfull-time120ECTSLanguage of instruction English40Study placesFinal degreeMaster of Science in Natural Sciences (MSc)Application period for academic year 2022/231st January to 27th March 2022tuition fee / semester:€ 363,361+ ÖH premium + contribution2 1 Tuition fees for students from third countries € 727,- per semester 2 for additional study expenses (currently up to € 83,- depending on degree program and year) What you can offer Your interest in breaking new ground in the development of vaccines and other medicines or in areas such as stem cell research and a desire to take on management responsibilities are excellent prerequisites for studying in this degree program. You want to be at the forefront of developing new technologies. You are not interested in a routine job, but want major challenges in research and development. You are a very curious individual who wants to examine things in fine detail and to this end you have the necessary patience to undertake the required steps in order to reach your goals. You know that you can achieve a lot on your own, but in a team you can achieve everything. English as the language of life sciences is part of your everyday working life. What we offer you You will be able to study and conduct research in state of the art lecture halls and laboratories. In addition, your education and research benefit from our close partnerships with the University of Vienna and the Medical University of Vienna. We have built a strong international network that provides you with the opportunity to study or conduct research at prestigious universities such as the King's College in London or the Stockholm University in Sweden. Numerous R&D projects in the degree program’s labs offer you the opportunity to participate in application-oriented practical research and to make valuable contacts for your future career. What makes this degree program special English-language degree program with focus in cancer research, immunology, drug discovery, human genetics and stem cellsR&D-Projects in cooperation with Universities and Companies: allergy research, cell-based test systems and cellular signaling pathways The Molecular Biotechnology Section is active in medical and pharmaceutical research. Your education benefits from the results of our already established research priorities cellular signaling pathways and immunology. In allergy research, we focus on food allergies as well as the pathological mechanisms of inhalational allergies, such as pollen allergies, with the help of epithelial cell culture systems. Thus, the degree program is not only a strong foundation for medical and pharmaceutical research, but also for a doctoral program at a university. What you will learn in the degree program This English language Master’s degree program, which is unique in Austria, offers you a balanced mix of molecular-biological subjects as well as key transversal skills.You will acquire knowledge und practical skills in the fields of molecular medicine and drug discovery.You will follow the main steps of modern drug development, from the first screening until the drug is approved.The degree program focuses on the following subjects: immunology, neurobiology, stem cells, pathology, as well as signaling pathways, pharmacology, and data analysis.You will improve your employment prospects with practical vocational auxiliary qualifications. You will learn more about innovation and the clinical development of drugs and will be able to move among the different cultures in the biotech industry. You will learn about bioethics as well as entrepreneurship and strategic business management. During your studies, you will refine your English, the international language of applied life sciences. In addition, you will learn interdisciplinary skills that are required in research and in management.The entire 4th semester of your studies is reserved for the research project, which you can undertake nationally or internationally. The studies will culminate in the Master’s thesis, comprising the results of the research project. Curriculum 1. Semesters LectureSWSECTSBioethics ILVBioethics ILVLector: Dr.in Mary Grace Wallis1SWS1ECTSLecture contentsCurrent (bio-)ethical topics relevant for the life sciences/pharmaceutical/biotech industry (see Learning Outcomes)Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, written group tasks, blended learning.LanguageEnglish11Bioinformatics ILVBioinformatics ILVLector: Mag. Dr. Walter Glaser2SWS2ECTSLecture contentsCommands in Linux Individual topics will be taken up and discussed in more detail, e.g: - biological sequences, sequence comparison - bioinformatic output formats/filesAssessment methodsContinuous assessment Continuous assessment including assessment of final projectTeaching methodsLectures, Powerpoint presentation, hands-on exercises and independent workLanguageEnglish22Clinical Drug Development ILVClinical Drug Development ILVLector: Dr. Astrid Christine Erber1SWS1ECTSLecture contents- Case studies: Clinical development of selected drugs (biopharmaceuticals and small-molecule drugs) - Classes of Pharmaceuticals - Clinical and epidemiological study designs - Outcomes and inclusion/exclusion criteria, special populations - Randomized Controlled Trials (RCTs): Randomization, Blinding and Placebos - Conduct of clinical trials - Data analysis and interpretation - Ethical aspects - The origins and principles of Good Clinical Practice (GCP) - International regulations (EMEA, FDA, ICH) - Interfaces: Regulatory Affairs and Pharmacovigilance, Marketing and Product Life Cycle Management - Special chapters: Generic drugs and biosimilars, orphan drugs and Advanced Therapy Medicinal ProductsAssessment methodsContinuous assessment Grading of participation and in-class exercises. Written exam at the end of the lecture course. Exam includes multiple choice questions as well as open questions.Teaching methodsLectures, small group discussions and in-class exercisesLanguageEnglish11General Pathology VOGeneral Pathology VOLector: Prim.Univ.Doz. Dr.med. Johann Feichtinger2SWS3ECTSLecture contentsStudents know and can explain the principles of general pathology, causes and development of pathological processes and diseases at the level of cells, tissues and the whole organism in detail. Students know and are able to describe the courses of illness and symptoms based on morphological alterations and clinicopathological correlations from the systemic/special pathology. In addition, students are familiar with and can explain the systematics and nomenclature of diseases as well as applied diagnostic and therapeutic strategies.Assessment methodsFinal exam Written multiple choice testTeaching methodsLecture (Powerpoint presentations, manuscript, glossary, mind maps) / Vorlesung (VL-Unterlagen als Powerpoint-Folien mit Schemata und Bildmaterial, VL-Manuskript, Glossar, Mind-Maps)LanguageEnglish23Intercultural Teams in Interdisciplinary Projects ILVIntercultural Teams in Interdisciplinary Projects ILVLector: Monika Frauwallner, DI Franz Gatterer, MBA, Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson1SWS1ECTSLecture contentsThe content of this integrated course, which is specially designed as the Kick-Off of the Master degree programme prepares the students from different countries, cultural backgrounds, universities, disciplines, and with individual life experiences to work together optimally in interdisciplinary, intercultural and international study and working environments. See the ‘Learning Outcomes' for further details.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, individual and group tasksLanguageEnglish11Medical Genetics VOMedical Genetics VOLector: Univ.-Prof.i.R. Dr. Christine Mannhalter2SWS2ECTSLecture contentsThe course will be divided in several parts: - summary of basic principles - discussion of molecular biological techniques including their limitations - discussion of several examples for genetic diseases, also in the context of useful and suitable methods (monogenetic, polygenetic, acquired). Students are encouraged to take the lead to preside over debates and scientific discussions on current scientific and/or ethical topics. At the end of the course, students undertake a quiz where they are encouraged to try to identify the cause of a disease.Assessment methodsFinal exam Preparation of a written manuscript to a specific topic, evaluation of the participation in discussions. (Seminar paper)Teaching methodsUse of Power Point presentation, regular discussions, use of quiz.LanguageEnglish22Medical Genetics Lab UEMedical Genetics Lab UELector: Ao.Univ.-Prof. Mag. Dr. Dietmar Abraham, Kay Holleis, BSc MSc, Andrea Krames, BSc MSc, Heidi Miedl, Ao.Univ.Prof. Dr. Martin Schreiber, Assoz.-Prof. Priv.-Doz. Mag. Dr. Karin Zins2SWS2ECTSLecture contentsVarious methods used in genetic analysis are explained and carried out practically. These include the reverse transcriptase polymerase chain reaction for the detection of leukemia associated fusion transcripts, gene amplification and hybridization to immobilized, allele specific oligonucleotides for the detection of mutations in the cystic fibrosis gene, and genotyping of a single nucleotide polymorphism (SNP) in a cohort of patients followed by statistical analysis of the association with disease risk.Assessment methodsContinuous assessment Immanent assessment of student's understanding of the subject, written laboratory report.Teaching methods- The theoretical basis of each of the analyses conducted in the laboratory is explained in a preceding seminar. - Students conduct genetic analyses according to detailed reports provided by the lecturers. - Laboratory results are discussed with lecturers at the end of each unit, and are summarized in a report whose structure corresponds to that of a scientific paper.LanguageEnglish22Molecular Genetics VOMolecular Genetics VOLector: FH-Prof. Dr. Thomas Czerny1.5SWS2ECTSLecture contents- Fundamental features of genetics and genetic engineering - Different levels of regulation of gene expression in pro- and eukaryotes - Transcriptional regulation (transcription in eukaryotes, transcriptional activation, properties of transcription factors) - Posttranscriptional regulation (splicing, transport, stability of mRNA, translational control) - Effects of chromatin (composition, histone modifications, regulation, epigenetics) - Examples from signalling pathwaysAssessment methodsFinal exam Written examsTeaching methodsLectures with Powerpoint presentationsLanguageEnglish1.52Molecular Immunology VOMolecular Immunology VOLector: Univ.Prof. Mag. Dr. Wilfried Ellmeier, Univ.Doz. Ao. Univ.Prof. Dr. Herbert Strobl2SWS3ECTSLecture contentsFundamental concepts of immunity, immunologic tolerance and autoimmunity, immunity to microbes, transplantation immunology, immunity to tumors, hypersensitivity disorders, allergy, congenital and acquired immunodeficiencies, immunotherapy and immunological methods.Assessment methodsFinal exam Written exam at the end of the lecture course. Exam includes multiple choice questions as well as open questions.Teaching methodsLectures, interactive discussions between students and lecturer.LanguageEnglish23Molecular Pathology VOMolecular Pathology VOLector: Ao. Univ. Prof. Mag. Dr. Wolfgang Mikulits, Ao. Univ. Prof. Mag. Dr. Ernst Müllner, Ao. Univ. Prof. Dr. DI Johannes Nimpf2SWS3ECTSLecture contentsIn this lecture course, initially the knowledge about the human genome is deepened. Building on that it is pointed out how genetic alterations can lead to disease. Further, methods to the identification of genetic diseases as well as methods for gene therapy are presented. The next part focuses on how aberrant molecular signal transduction can contribute to tumor development and metastasis. This is complemented by presentation of in vivo and in vitro tumor models. The final part is concerned with the topics of tissue printing and cell engineering. This is complemented by presenting novel developments in stem cell biology in normal as well as tumor tissues. Accompanying, in all parts important methods like flow cytometry, migration assays, fluorescence microscopy and blood cell analysis are addressed.Assessment methodsFinal exam Written exam after the end of the course; open questions, no multiple choice.Teaching methodsMainly powerpoint slides pointing out additional weblinks to literature sources, web-based texts and video content.LanguageEnglish23RNA VORNA VOLector: FH-Prof. Dr. Herbert Wank1SWS2ECTSLecture contentsRNA fundamentals, RNA structure, catalytic RNAs, RNA processing, RNA splicing, RNA editing, riboswitches, RNA applications, non-coding RNAs, RNAi, RNA world, SELEXAssessment methodsFinal exam Written exam at the end of the course.Teaching methodsLectureLanguageEnglish12RNA Analysis Lab VORNA Analysis Lab VOLector: Kay Holleis, BSc MSc, FH-Prof. Dr. Herbert Wank3SWS3ECTSLecture contentsRNA methods: - Northern blot (glucose/galactose metabolism in yeast, RNA extraction from yeast, denaturing RNA agarose gel, RNA transfer, specific oligonucleotide hybridization, band detection, quantitative PCR) - EMSA (in vitro transcription with T7 RNA polymerase, RNA purification, RNA folding, native polyacrylamide gel electrophoresis, RNA staining using methylene blue, detection of RNP complexes) - RNA stability (temperature dependence, pH dependence, RNAses)Assessment methodsContinuous assessment Continuous assessment - presence, motivation, participation, practical skills (results), written report.Teaching methodsLaboratoryLanguageEnglish33Scientific Communication I ILVScientific Communication I ILVLector: Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson2SWS3ECTSLecture contentsThe scientific and ethical content (see the ‘Learning Outcomes' for specific details) of this course aligns with the aims of the Master degree programme, and by working closely with other lecturers compliments the content of the other courses.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, written individual and group tasks, blended learning.LanguageEnglish23Vascular Biology VOVascular Biology VOLector: Ass.Prof. MMag. Dr. rer. nat. Alice Assinger1SWS2ECTSLecture contentsStudents are able to decribe the three main areas: hematology, vascular biology and vascular pathology. Hematology deals with the following topics: 1. erythrocytes (structure, cytoskeleton, hemoglobin, gas exchange, erythrocyte breakdown, iron metabolism, blood groups) 2. leukocytes (morphological leukocyte differentiation) 3. Platelets (structure, activation, adhesion, aggregation, interaction with cells or with the extracellular matrix) 4. Hemostasis (plasmatic coagulation, cell-based model of coagulation, fibrinolytic system, inhibitor systems, blood coagulation tests) 5. Laboratory diagnosis of blood (sample collection, plasma/serum, sample composition/sources of error, clinical chemistry, red/white blood count, blood group serology) 6. Hematological diseases (reactive changes of the erythrocytes/leucocytes/platelets, disorders of hemostasis) / Vascular biology deals with: 1. an overview of the vascular system (terms, structure, blood vessel system / lymphatic system) 2. development of the blood vessels (vasculogenesis, angiogenesis, significance and function of specific angiogenic growth factors) 3. the endothelium (biology of the endothelial cell, structure of endothelia, endothelial species) 4. the functions of the endothelium (regulation of vascular tone, endothelium and cell adhesion, endothelial dysfunction) Vascular pathology describes: 1. the role of the endothelium in the acute inflammatory response (systemically explained by the example of sepsis and locally using the example of "acute lung injury" and 2. atherosclerosis described as a chronic inflammatory vascular disease (risk factors, lipid metabolism, atherogenesis, pathophysiology of unstable plaque / plaque rupture, animal models in atherosclerosis research).Assessment methodsFinal exam Exam; single-choice questions and essay about a topic.Teaching methodsReading of primary literature, lectures with power point and flip chart, self-study.LanguageEnglish12 2. Semesters LectureSWSECTSBiologicals VOBiologicals VOLector: Dr. Klaus Rumpel1SWS1ECTSLecture contentsThe lecture course "Biologicals" gives an overview over the most important aspects of biotherapeutics (= biologics) which is the fastest growing type of drug gaining more and more importance. The focus of the course is the discovery research of therapeutic concepts enabled by engineering of biologics, bioprocess development of biologicals, and manufacturing aspects. Major differences and therapeutic aspects differing between small molecule drugs and biologics are discussed; examples of major classes of biologics are presented as case studies. Discovery and engineering of therapeutic monoclonal antibodies are discussed in more detail as this class of therapeutics reflects the biggest class amongst many other biologicals. Approaches and technologies for biopharmaceutical manufacturing and purification will be discussed; major aspects and challenges of protein analytics and physicochemical characterization of biologics will be highlighted.Assessment methodsFinal exam Written exam in the last lectureTeaching methodsLectureLanguageEnglish11Drug Screening VODrug Screening VOLector: Michael Nagl, Dr, Prof.(FH) Mag. Dr. Christoph Wiesner1SWS1ECTSLecture contentsStudents learn how to isolate natural drugs (small molecules) from plants or how to produce biologics. Course content also includes different in vitro screening methods, HCS, HTS (including target-and phenotype-based drug discovery).Assessment methodsFinal exam Final written exam (100%)Teaching methodsLectureLanguageEnglish11In Silico Biology VOIn Silico Biology VOLector: Mag. Dr. Walter Glaser3SWS3ECTSLecture contentsBioinformatics topics will be addressed and the practical solution of biological problems with bioinformatics tools will be discussed. The topics include: - the Human Genome (Genome analysis: SNPs, Variant Discovery) - biological batabases - data formats - protein domains, regulatory patterns - non-coding RNA prediction - gene set analysisAssessment methodsFinal exam Written test on the theoretical part (50%), report (50%)Teaching methodsLectures, Powerpoint presentation, discussion and independent hands-on exercises with bioinformatics toolsLanguageEnglish33Infection Biology VOInfection Biology VOLector: Priv. Doz. Dr. rer. nat. habil. Holger Scholz, Professor und Direktor, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda2SWS2ECTSLecture contentsIn this lecture, beside the basics of medical microbiology, the complex interactions between pathogens and the human host are presented and the molecular, cellular and immunological aspects of this interaction are explained. Strategies developed by bacteria, viruses, fungi and parasites to colonize, invade, survive, reproduce and spread are discussed. Furthermore, the cellular and systemic effects on the host, the host's defence mechanisms and the clinical manifestations of the infectious diseases are shown. In addition, principles of the diagnosis of infectious diseases as well as antimicrobial and antiviral treatment options are explained and concepts behind the development of novel diagnostic tools, drugs and vaccines for future prevention and therapy of infectious diseases are presented. The lecture is rounded off by a detailed presentation of selected infectious diseases using clear visual material and a presentation of own research activities.Assessment methodsFinal exam Written exam in the end of the lecture courseTeaching methodsLectureLanguageEnglish22Innovation in Biotechnology & Start-Ups ILVInnovation in Biotechnology & Start-Ups ILVLector: DI Franz Gatterer, MBA2SWS2ECTSLecture contentsDefinitions and meaning of Knowledge and the management of knowledge in a knowledge-driven society in general and in the field of Biotechnology in particular with heavy focus on phases of Research and Development (R&D). What is it? Definitions? Perspectives: The human and the data, principles, types, processes, concepts, tools and practice. From Invention (Research/Technology) to Innovation: The Management of Innovation. Definitions and basics, the process of Innovation Management, the strategic dimension of innovation. Innovation analyses/assessment and organisational aspects of implementation. From a business idea to a business plan: The story of a business plan and its elements (externally and internally). The business idea, the vision/mission statement and it's reflection in a certain product/service, the targeted market with its characteristics (such as customers, competitors, partners, etc.), the financials, the legal environment, the organisation needed to drive business implementation, the plan for implementation. The four phases for business-plan development and its implementation: Build hypotheses derived from a business idea, feedback, maturing it through “friendly customers”, incorporate results and show business plan to real customers, to real investors (or funding organisations), if successful, go through foundation process, business start and ongoing improvements. Useful Tools: Porter Model – 5 Forces, SWOT Analyses; Life-Cycle Analyses; Canvas Business Model Concept, BP-Calculation templates, BP templates; Risk Analyses.Assessment methodsFinal exam Evaluation of group results (a complete business-plan plus a BP presentation). In addition, individual interviews with students about their results facilitates quality assurance respectively control at an individual level. (Group work)Teaching methodsStudent-centred methods: project work in fixed groups, presentations, partly: flipped class-room approach, debates, discussions, written tasks.LanguageEnglish22Intellectual Property & Patent Law VOIntellectual Property & Patent Law VOLector: Dr. Irene Fialka, CMC, Mag. Dr. Manuela Loidl1SWS1ECTSLecture contents• Which forms of protection of intellectual property are available? – trademark, industrial design, copyright, utility model, complementary protection certificate, patent • History of patent rights • What is a patent? – effects of a patent – what can be patented and what is excluded from patent protection? – what are the prerequisites for patent application/protection? – How to define an inventor? Rights and obligations of employee inventors • From application to patent grant – structure of a patent application – application and granting processes - protective reach and duration – legal measures – fees and costs – where to apply for a patent • Rights of patent owners and legal measures • International agreements (EP, PCT), important national differences • Biopatents – legal framework, important decisions • Freedom to Operate • Espacenet and how to use it for patent research • Patent lawyer - the profession • Fundamentals in copyright • Fundamentals in industrial design • Fundamentals in trademark • Strategies and decision making • Important agreements– MTAs, CDAs, licensing contracts • Licensing contracts - fundamental principles, important clauses – FranchiseAssessment methodsContinuous assessment Written exam at the end of the course.Teaching methodsLectures with interactive elements and discussions, actual cases will be discussed in more detail.LanguageEnglish11Molecular Pathology Lab UEMolecular Pathology Lab UELector: Kristina Breitenecker, MSc, Ao. Univ. Prof. Mag. Dr. Wolfgang Mikulits, Ao. Univ. Prof. Mag. Dr. Ernst Müllner3SWS3ECTSLecture contents- Various tissue staining techniques; patho-histological evaluation of tumor tissue samples and photographical documentation; characterization of blood by flow cytometry; determination of leucocytes in blood smears; blood sugar measurements in oral glucose-tolerance tests - Isolation of chicken granulosa cells from pre-ovulatory follicles; fluorescence microscopy of thin sections of follicles; stimulation of transgenic fibroblasts (ApoER2+Dab1 or VLDLR+Dab1) with Reelin followed by detection of Dab1 phosphorylation by immunoprecipitation and Western blotting - Proliferation kinetics and clonogenic assays; cell migration and wound healing assays; cell migration assays using transwellsAssessment methodsContinuous assessment Immanenter Prüfungscharakter durch permanente Beobachtung der Mitarbeit und des persönlichen Engagements; Qualität der Datenauswertung und Dokumentation im schriftlichen ProtokollTeaching methodsPractical laboratory course accompanied by introductory seminarsLanguageEnglish33Molecular Virology VOMolecular Virology VOLector: Ao.Univ.Prof. Dr. Dieter Klein, Dr.rer.nat. Christoph Metzner1SWS2ECTSLecture contentsReplication cycle of important virus families, pathogenetic mechanisms of important viruses, anti-viral strategies, and importance of viruses in molecular biology and medicine.Assessment methodsFinal exam Written examinationTeaching methodsInteractive LectureLanguageEnglish12Scientific Communication II ILVScientific Communication II ILVLector: Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson2SWS2ECTSLecture contentsThe scientific and ethical content (see the ‘Learning Outcomes' for specific details) of this course aligns with the aims of the Master degree programme, and by working closely with other lecturers compliments the content of the other courses.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, debates, discussions, written individual and group tasks, blended learning.LanguageEnglish22Signalling Pathways VOSignalling Pathways VOLector: FH-Prof. Dr. Thomas Czerny1SWS2ECTSLecture contentsImportant signalling pathways of the cell (e.g. MAP kinase-, GPCR-, Nuclear Hormone Receptor-, NF-kB-, Jak/Stat-, Wnt-, Hedgehog-, Tgfß-, Apoptosis-, PI3K/Akt- and stress pathways) are presented together with their effects on gene expression and other functions of the cell. In addition the crosslinks with other pathways are discussed. Techniques for the analysis of signalling pathways are also presented.Assessment methodsFinal exam Written ExamTeaching methodsLectures with Powerpoint presentations, Discussion of selected chaptersLanguageEnglish12Signalling Pathways Lab UESignalling Pathways Lab UELector: Andrea Krames, BSc MSc, Dr.in Elisabeth Riegel3SWS3ECTSLecture contentsMethods for the manipulation and the analysis of signalling pathways in cell culture are applied, broadening the knowledge on specific pathways. The applied methods are transient transfection in cell culture, reporter constructs with gfp and luciferase, overexpression of activators/repressors (including RNAi), Western analysis of cellular extracts, analysis of phosphorylation, fluorescence microscopy of labelled proteins and pharmacologic manipulation of the pathways.Assessment methodsFinal exam Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experiments. (Seminar paper)Teaching methodsLaboratory workLanguageEnglish33Stem Cells VOStem Cells VOLector: Dr. Arabella Meixner1.5SWS2ECTSLecture contentsReports about stem cells and their usage in biomedical research has raised several important key questions about their capacity to use for stem cell-based therapies to cure diseases. Our course starts with an overview about stem cell biology, where to find stem cell and might there be a different o stem cells isolated from various organisms, such as axolotl. We start to understand how an organsims is developing and where to find stem cells in a human body. For a deeper knowledge in stem cell biology we learn about induced pluripotent stem cells and the development of mini organs/organoids. We discuss the potential usage of stem cells in clinical applications, the importance for society and relevant ethical aspects. Finally, we present latest key news and views about recently published stem cell research breakthroughs.Assessment methodsFinal exam Written examTeaching methodsInteractive lectures with discussions using Power point presentation and the blackboardLanguageEnglish1.52Stem Cells Lab UEStem Cells Lab UELector: Mag. Dr. Thomas Dechat, Nina Malajner, MSc, Dr. Arabella Meixner2.5SWS3ECTSLecture contentsThe course teaches the fundamentals of the culture of murine embryonic stem cells and induced stem cells and practical applications. Different cultivation possibilities for ESC and the control of the stability of the cultures in the undifferentiated state will be learned (morphological analysis, alkaline phosphatase assay). Targeted differentiation using the embryoid body (EB) model will be learnt and in addition, experimental investigations will be carried out on how different inhibitors or activators influence differentiation. The formation of EB is analyzed by light microscopy. Using an example, the use of CRISPR/Cas in stem cells will be practiced.Assessment methodsContinuous assessment Continuous assessment. The grade is comprised of the following sections: attendance, motivation, cooperation, written reportTeaching methodsPractical laboratory courseLanguageEnglish2.53 Electives 1 (1 ECTS of your choice)LectureSWSECTSDrug Discovery SEDrug Discovery SELector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of Drug Discovery are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsFinal exam Participation in discussion (Seminar paper)Teaching methodsSeminarLanguageEnglish11Molecular Immunology SEMolecular Immunology SELector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of Molecular Immunology are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsContinuous assessment Participation in discussion (Seminar paper)Teaching methodsSeminarLanguageEnglish11RNA SERNA SELector: FH-Prof. Dr. Herbert Wank1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of RNA research are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsContinuous assessment Participation in discussionTeaching methodsSeminarLanguageEnglish11 Electives 2 (2 ECTS of your choice)LectureSWSECTSTherapeutic Strategies VOTherapeutic Strategies VOLector: Doz. Mag. Dr. Wolfgang Sommergruber1SWS2ECTSLecture contentsTherapeutic strategies based on signal transduction pathways in health and disease provides a detailed view of the underlying molecular biology of selected diseases and novel treatment modalities with a particular focus on oncology. Clinical failures and validity of targets, Extracellular signaling (endocrine – paracrine – autocrine; Multitype) - Mechanisms of signal transduction and the determination of the fate of a cell - Intracellular signal-transduction (signaling by phosphorylation and GTP-binding) - PD-1/PD-L1 and CTLA-4 signaling in immune cells - Molecular mechanisms of EMT - Ligand-binding and effector specificity of receptor proteins - Acetylcholine: Same signal can lead to different effects in cells of different tissues - Hormones: Small lipophilic molecules and their intracellular receptors; hydrophilic and lipophilic hormones and their cell-surface receptors - Hormone receptors (retinoid-x-receptor; PR, GR, AR and ER receptors) - Hashimoto's thyroiditis, Graves' disease - Nuclear receptors - Prostaglandin (PG) Biosynthesis (COX1, 2; COX inhibitors) - Prostaglandin signal-transduction pathways - Insect and snake venom (PLA2) - Prostaglandins in breast cancer and endometriosis (autocrine and paracrine actions of PEG2 and PEF2a - Biphasic activation of FGF-9 by PGE2 - Phagocytic ability of macrophages and PEG2 - StAR aromatase and aromatase inhibitors - G protein-coupled receptors - Ion-channel receptors - Tyrosine kinase-linked receptors - Receptors with intrinsic enzymatic activity - EGFR (mechanisms of EGFR dysregulation - Therapeutic concepts, types of biomarkers - Molecular mechanisms of oncogene addiction and clinical resistance - Compensatory pathways in oncogenic kinase signaling and resistance to targeted therapies (EGFR, BRAF, SMO) - Dual-specificity phosphatases: Critical regulators with diverse cellular targets - The hedgehog and Hippo pathway in development and disease - Fusion proteins of ALK and their contribution to tumorigenesis - Tyrosine kinase-linked receptors - Mechanisms to die: Immunogenic cell death (ICD).Assessment methodsFinal exam Written exam and a short oral presentation (5 minutes, FlipChart) + feedbackTeaching methodsOral presentations with PowerPoint slides, printed handouts will be provided (if requested), short presentations by students on selected topics (FlipChart); see also Assessment Methods.LanguageEnglish12Vaccine Development VOVaccine Development VOLector: Dr. Shailesh Dewasthaly1SWS2ECTSLecture contentsStudents know and can explain the currently used vaccines and the approaches to the development of vaccines against known and emerging infectious diseases. Furthermore, students can describe how the vaccines are being developed from an ‘industrial perspective' and can appreciate the complexities involved in development of vaccines all the way to licensure of the vaccines. Post licensure effectiveness of the vaccines are also discussed. Students gain a deeper understanding of the development and production of vaccines from the laboratory to the clinical trials by carrying out independent literature research and communicating their findings with supporting media (peer teaching), using current globally significant vaccines as examples.Assessment methodsContinuous assessment Continuous assessment, assignment and presentationTeaching methodsInteractive lectures with Powerpoint slides and active participationLanguageEnglish12 3. Semesters LectureSWSECTSAllergies & Autoimmune Diseases VOAllergies & Autoimmune Diseases VOLector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS2ECTSLecture contentsIn this lecture course the molecular and cellular mechanisms of allergies and other hypersensitivity reactions are explained and the symptoms, causes and risk factors of allergic diseases are described. Furthermore, advantages and disadvantages of current diagnostic tests and therapeutic possibilities are discussed and strategies for improvement of diagnosis and therapies of allergies are introduced. This lecture course also explains the pathomechanisms underlying autoimmune disorders and describes determinants (such as genetic predisposition or environmental factors) that influence the development autoimmunity. In addition, the pathogenesis, clinical manifestation and the treatment possibilities of a few selected autoimmune diseases (e.g., Rheumatoid Arthritis, Multiple Sclerosis) are discussed. Furthermore, this lecture course also highlights similarities and differences between allergies and autoimmune disorders.Assessment methodsFinal exam Written exam after the last lectureTeaching methodsLectureLanguageEnglish12Computational Data Analysis ILVComputational Data Analysis ILVLector: Mag. Dr. Walter Glaser2SWS2ECTSLecture contents1) Acquire knowledge on selected bioinformatics chapters (Next Generation Sequencing, ChIP-Seq, RNA-Seq), and 2) Application of relevant bioinformatics tools to analyse the associated data.Assessment methodsFinal exam 100 % Report in which students have to analyse RNA-Seq Data/ChIP-Seq DataTeaching methodsIntroductions and explanations (lecture), Exercises using the computerLanguageEnglish22Drug Design VODrug Design VOLector: Dr. Klaus Rumpel2SWS2ECTSLecture contentsAt the center of this course is the drug and its interaction with target proteins. Methods for determination of protein structures and characterization and quantification of protein ligand interactions are presented. In addition strategies and methods for the optimization of these interactions are discussed (lead optimization, rational design). Furthermore, aspects of pharmacokinetics (ADME, prodrugs) are presented. The underlying principles are demonstrated by selected examples.Assessment methodsFinal exam Written exam in the last lectureTeaching methodsLectures (Powerpoint presentations and downloads)LanguageEnglish22Gene Therapy VOGene Therapy VOLector: Ao.Univ.Prof. Dr. Dieter Klein, Dr.rer.nat. Christoph Metzner1SWS2ECTSLecture contentsPrinciples of gene therapy, overview on applications of gene therapy, gene transfer methods, methods for gene transfer estimation, characteristics of different viral vector systems, non-viral vector systems, lenti-/retroviral vectors, adenoviral vectors, adeno-associated viral vectors, applications of gene therapy for different diseases, problems and perspectives.Assessment methodsFinal exam Written examinationTeaching methodsInteractive lectureLanguageGerman12Mass Spectrometry ILVMass Spectrometry ILVLector: Claudia Ctortecka, MSc, DI Dr. Johannes Stadlmann2SWS2ECTSLecture contentsDuring the "hands on" laboratory every student excises a band containg a protein out of a 4-20% SDS-PAGE (Tris/Glycine) gradient gel. Purification, reduction and alkylation of Cysteines, o/n digestion with Trypsin, next day spotting onto a MALDI target, and generation of a PMF mass spectrum with MALDI-TOF and MSMS spectra of the most intense peptides. Subsequently identification of the protein with database search algorithms. The theoretical part provides an introduction into the basic principles of proteomics: sample preparation & fractionation (1D and 2D GE, HPLC, CE, SCX RP and affinity chromatography, difficulty of contamination e.g. keratins, SDS, salts). Explanation of the principles of mass spectrometry: ion sources (MALDI, ESI), types of mass spectrometers (TOF, quadrupole, ion trap, FT ICR) and the respective combinations e.g. MALDI-TOF/TOF etc. Resolution R and mass accuracy dm/m (ppm). Improvement of the latter by delayed extraction & reflectron for MALDI-TOF. Isotopic distribution, single and multiple charged ions (ESI). PMF (peptide mass fingerprinting), principles of data base analysis of mass spectra. Collision induced dissociation CID, MS/MS analysis and de novo sequencing. In addition, an introduction into the methods of quantitative proteomics as well as the analysis of post-translational modifications will be included, as well as an introduction into the application of mass spectrometry (and other technologies) to further analytical questions in addition to proteomics, e.g. metabolomics, lipidomics, drug development and environmental research. Finally, students present an exposé with their own concepts how to tackle a specific analytical question, using the methodology discussed in the course.Assessment methodsContinuous assessment Active course participation, results of written test and/or oral examination, evaluation of laboratory report and exposé on potential research project using mass spectrometryTeaching methodsWet laboratory work, tutorial on all theoretical contents, video material, data analysis on computer, critical evaluation of data.LanguageEnglish22Master Project Seminar ILVMaster Project Seminar ILVLector: FH-Prof. Mag. Dr. Beatrix Kuen-Krismer1SWS1ECTSLecture contentsDuring this course, the students independently - with the support of the Master's Thesis Coordinator - seek a research project in an inter/national life science research institution or research company, whose content, quality and duration is suitable to write a high-quality master's thesis. Together with the direct supervisor of the research project, the students prepare a project plan for the course of the research project. The plan contains the project goals, the problem definition and the method spectrum to be used. In small groups, the students present the elaborated plans of their planned research projects to their peer group as well as their motivation to carry out this research project. The group discusses and reflects on the presented problems, strategies and methods and gives their feedback.Assessment methodsContinuous assessmentTeaching methodsActivating Methods: e.g. presentations, discussions …LanguageEnglish11Molecular Immunology Lab UEMolecular Immunology Lab UELector: Kay Holleis, BSc MSc, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda3SWS3ECTSLecture contentsIn the Molecular Immunology laboratory the theoretical immunological knowledge is deepened and practically applied to research problems from the field of allergy research. Students work in small groups of 2 to 3 people on a scientific research question. As a team they have to find the best way to answer the research question, they have to design and perform the experiments using state-of-the-art immunological and molecular biological methods such as ELISAs, SDS-PAGE, immunoblotting, PCR, microscopy and flow cytometry. Finally, each student writes a laboratory report in the format of a scientific publication, in which the background of the research topic is summarized and the experimental work, the results and the conclusion are described.Assessment methodsContinuous assessment Continuous assessment, active participation, reportTeaching methodsLaboratoryLanguageEnglish33Molecular Neurobiology VOMolecular Neurobiology VOLector: Dr.phil. Dr. med.univ. Karl-Heinz Huemer2SWS3ECTSLecture contentsStudents are able to explain membrane physiology, the development of action potentials, electrotonic and saltatoric conduction, synapses, important transmitters and the resulting pharmacological modulation, temporal and spatial integration, pre- and postsynaptic inhibition, as well as, motor functions of the spinal cord, basal ganglia, cerebellum, and cortex including disorders caused by lesions in these regions, the structure and function of the autonomic nervous system including effects on important organs, and the function of the sensory systems.Assessment methodsFinal exam Written examTeaching methodsLectureLanguageEnglish23Molecular Pharmacology ILVMolecular Pharmacology ILVLector: Mag. Dr. Gerda Brunhofer-Bolzer, MSc.2SWS3ECTSLecture contentsStructure and function of drug targets on the molecular level as well as their role as regulators of cell function, the prodrug strategy, and most frequently prescribed drugs for the treatment of human diseases (e.g. background of a disease, mechanism of action, important side effects).Assessment methodsFinal exam Written examination at the end of the course, evaluation of the tasks provided during the courseTeaching methodsEach topic is introduced and necessary information is provided through didactic lectures and e-learning methods. Subsequent lectures focus on the use of this information (e.g. discussion of research papers or research problems, student/poster presentations).LanguageEnglish23Strategic Business Management ILVStrategic Business Management ILVLector: DI Franz Gatterer, MBA2SWS2ECTSLecture contentsThe Strategic Business Management course is built on four pillars. I) Leadership and Management of enterprises/projects for Industry and/or Academia The major drivers for modern business management are addressed (innovation, globalisation, market dynamic, etc.). From there, the difference of management and leadership will be explained. Build on fundamentals of systemic thinking, reflected for the background of complexity, innovation and change, the differences of working “on a system” (leadership) and working “in a system” (management) will be explained and discussed. Pros/Cons will be elaborated for different environments. The different traditional management styles will be enhanced by leadership approaches and mapped to leading people (individuals) and organisations (teams) in a dynamic branch. II) Strategic Thinking – Strategy Development (Strategic Concepts – from Vision/Mission to Strategy) and its Elements in a Holistic Approach A company's identity through vision, mission and corporate culture as framework for its strategy is the baseline of this chapter. A vision and its important function for organisations and its individuals as initial impulse for orientation and order, as success driving function for alignment and motivation will be explored. The effectiveness of visions in the sense of positioning, top down implementation, targets and continuous communication is analysed. The Porter Model is explained and used to show different strategy types (e.g. product market Strategies (Ansoff), competitive strategies, development strategies). III) The Operational Perspective of Business Management – Strategy Implementation (Management-system, Framework and Indicators) The importance, characteristics and elements of management systems are explained and elaborated by analysing different models such as Balanced Scorecard, EFQM Model and/or ISO 9001:2015. It is shown, how a set of policies, processes and its alignment to the organization is targeted to achieve company´s objectives. IV) Adopted Company – A capstone project, where students apply the learning outcomes by analysing all elements learned in I-III The strategic analysis of a selected, “adopted” company builds the final capstone of the lecture course. Students analyse all relevant elements of a company (vision, mission, values/culture, strategic approach and goals related research, product portfolio, human resources, market, sales, etc.) and derive strategic recommendations for the company to successfully mature its market position. The entire course content will be critically addressed by future requirements as well as trends and developments in biotechnology business areas.Assessment methodsContinuous assessment Evaluation of group results (results of “adopted company” analyses and suggestions). In addition, individual interviews with students about their results facilitates quality assurance respectively control at an individual level.Teaching methodsStudent-centered methods: project work in fixed groups, presentations, partly: flipped class-room approach, debates, discussions, written tasksLanguageEnglish22Toxicology Lab UEToxicology Lab UELector: Kay Holleis, BSc MSc, Dr.in Elisabeth Riegel3SWS3ECTSLecture contentsThe toxicological and therapeutic potential of a small molecule drug will be estimated with a variety of cell based test systems. On the one hand the activating potential of the small molecule on a specific pathway (heat shock response pathway) is analysed and on the other hand possible cytotoxic effects are estimated in a concentration-dependent manner. A broad variety of assays is provided for the students including luciferase reporter assays, Western blot, qPCR, flow cytometry, ELISA and general viability assays. The students themselves select suitable methods.Assessment methodsContinuous assessment Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experimentsTeaching methodsPractical course with independent performance of the experiments.LanguageEnglish33Tumour Biology VOTumour Biology VOLector: Ao. Univ. Prof. Mag. Dr. Jozefa Gadek-Wesierski2SWS3ECTSLecture contentsThis course offers an overview of the changes and disturbances of the correct regulation of the cell cycle progression and of the dysfunction of the induction and execution of the programmed cell death and metabolism which occur during the malignant transformation and finally lead to cancer development. Moreover, it includes the description of the most important post-translational modifications of proteins and their role in the functional regulation of distinct proteins involved in the signal transduction. It gives an understanding of the expression and the function of tumour suppressor genes and proto-oncogenes as well as the changes of their regulation (inhibition or constitutive activation) that essentially contribute to cancer development. This course aims at giving students an overall view of the complexity of the carcinogenesis that encompasses cooperation between a variety of changes, dysfunctions and pathways. This course includes several topics depicting the involvement of genetic and external factors in carcinogenesis. It also gives an understanding of the role and balance between distinct suppressors and oncogenes in angiogenesis and metastasis.Assessment methodsFinal exam Evaluation of regular participation and active cooperation as well as final written examinationTeaching methodsEvaluation of regular participation and active cooperation as well as final written examinationLanguageEnglish23 Electives 3 (1 ECTS of your choice)LectureSWSECTSComputer-Assisted Systems & Data Integrity ILVComputer-Assisted Systems & Data Integrity ILVLector: DI Dr. Timo Kretzschmar1SWS1ECTSLecture contentsIntroduction to the fundamentals of validation and operation of computerised systems in the pharmaceutical industry and regulative environment as required to be compliant with the current EU regulations • GxP requirements to be considered • Quality risk management • Qualification / validation of systems ... • Management of deviations and changes • Corrective and preventive actions • Appropriate documentation • Navigation in a multivalent working environment • Typical systems as examples, introduced from the systemic point of view (ERP, MES, diverse databases, LIMS, cloud systems, data storage and retention systems and procedures like electronic archiving and backup procedures) • Practical examples as the core of explanations applied to the legislative demandsAssessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsLectures combined with discussion, based on practical examplesLanguageEnglish11Regulatory Affairs & Pharmacovigilance ILVRegulatory Affairs & Pharmacovigilance ILVLector: Mag.rer.nat Sabina Benes, Mag.pharm. Dr. Regina Lauer1SWS1ECTSLecture contentsRegulatory affairs, the main contact point to health authorities and, pharmacovigilance, patient safety post clinical development, see Learning Outcomes for specific details.Assessment methodsContinuous assessmentTeaching methodsInteractive lectures with discussionsLanguageEnglish11 Electives 4 (1 ECTS of your choice)LectureSWSECTSScientific Method: Drug Discovery SEScientific Method: Drug Discovery SELector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel1SWS1ECTSLecture contentsIn this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Drug Discovery), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency, Finally each group presents its research project.Assessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsSeminarLanguageEnglish11Scientific Method: Immunology SEScientific Method: Immunology SELector: FH- Prof.in Mag.a Dr.in Marianne Raith, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Immunology), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency. Finally each group presents its research project.Assessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsSeminarLanguageEnglish11 4. Semesters LectureSWSECTSMaster Exam APMaster Exam AP0SWS2ECTSLecture contentsThe Master's examination represents the final examination of the Master's program before an examination committee of experts. The students present their Master's thesis in the form of a lecture. The students are questioned about their presentation and they defend the contents and conclusions of their Master's thesis. They are asked to cross-connect the topic of their Master's thesis to relevant subjects of the degree program. The students reflect and discuss current research topics from the main fields of the Master's program with the examination committee of experts.Assessment methodsFinal exam For the presentation of the Master's thesis up to 40 points are awarded by the examination committee. Up to 30 points are awarded for the subsequent discussion on the presentation. Up to 30 points are also awarded for the discussion of current research topics from the main areas of the Master's program. The sum of these points gives the overall grade for the Master's examination.Teaching methodsActivating Methods: presentations and oral examLanguageEnglish02Master Thesis MTMaster Thesis MT0SWS28ECTSLecture contentsWriting an English language Master‘s thesis.Assessment methodsFinal exam Assessment by experts.Teaching methodsLaboratory and literature researchLanguageEnglish028Semester dates Summer semester 2022: 14th February 2022 to 30th July 20223 Winter semester 2022/23: 5th September 2022 to 4th February 202333 depending on the lab coursesNumber of teaching weeks 18 per semesterChoosing Electives Electives can only take place when enough students register for them. An admission procedure may take place if the number of interested students exceed the course limit.Times Mon. to Fri. all day; some vocational subjects also held on Sat.Language of instruction EnglishCurriculum until 2019Expiring Curriculum Open Courses You also have the possibility to choose „open courses“ from other degree programs and departments. Registration details may be found here (currently only in German). Career opportunities As a graduate, you will mainly be engaged in research and development in your future employment. You can undertake a life science PhD at an Austrian or international university. You are qualified to lead lab or research groups. In addition, you have the entrepreneurial expertise to set up your own start-up. You will work in the following industries and sectors:Industry (Pharma, Biotech, Medtech, Food industry, etc.)Medical research (e.g. tumor biology, vaccine development, degenerative diseases) Research and development departments of established pharmaceutical (life science) companies as well as biotech start-ups Universities, non-university research establishments (e.g.: The Austrian Academy of Sciences, Austrian Institute of Technology, etc. ) and Universities of Applied Sciences Analytical laboratories in the industry and clinicsVeterinary research and developmentGovernment agencies Internship at the renowned Massachusetts Institute of Technology Florian Kabinger completed the English Master program Molecular Biotechnology in 2020. Equipped with the Austrian Marshall Plan Scholarship, he went abroad to do his internship at the renowned Massachusetts Institute of Technology (MIT). And he will continue his top-class education: due to his achievements during his studies in Austria and the USA he was accepted for the tri-institutional PhD program of the Weill Cornell Medicine, Rockefeller University, and the Memorial Sloan Kettering Cancer Center in New York. Admission Admission requirements Bachelor’s certificate, Diploma certificate or equivalent certificate from abroad Bachelor’s degree or equivalent similar qualification from an institute of higher education with a total of 180 ECTS credits in the disciplines of molecular biology, biology with a focus on genetics and/or microbiology, biotechnology, pharmacy, medicine, food biotechnology or biomedical sciences with at least: 30 ECTS credits in Biology, where at least 20 ECTS credits must be in molecular biology, genetics, cell biology, microbiology, genomics and/or biotechnology and at least 10 of these ECTS credits must be in biological labs/practical courses during the degree program, 15 ECTS credits in chemistry (general, analytical, physical, organic, bioorganic, biochemistry), and 6 ECTS credits in mathematics, statistics, informatics. In order to assess whether you have the required ECTS credits for the Master’s degree program Molecular Biotechnology, please complete the linked table, also add existing or missing credits as part of the application - please click HERE to fill out the table to open the file (PDF 1,1 MB)If the applicant graduated from an education system, which does not use the ECTS credit system, it is the applicant’s responsibility to demonstrate ECTS-equivalence.If you meet the admission requirements and if the ECTS credits are only slightly below the required number, it will be decided on a case-by-case basis whether the additional ECTS credits can be compensated by additional examinations in order to allow admission to the degree program.Equivalent certificate from abroad - Equivalence is determined by international agreements, validation or in individual cases a decision by the head of the academic section.Information for applicants with non-Austrian (school) certificates (PDF 145 KB)Regulation for the admission of third country citizens (PDF 233 KB)English language proficiency at CEFR level C1The program is conducted entirely in EnglishStudents who have obtained their higher education entrance qualification and Bachelor's degree in the EU, EEA or Switzerland do not require proof of their English language skills.Students who speak English as their first language must prove their nationality, place of birth and length of stay in a country with English as their official language.All other students must provide written proof of their English proficiency, e.g. by a currently valid certification of one of the following tests: Test of English for International Communication (IELTS) 7-9Cambridge English Advanced (CAE)Cambridge English Proficiency (CPE)Test of English for International Communication (TOEIC) 880-990Test of English as a Foreign Language, internet-based test (TOEFLiBT ) 110-120UNICERT (III) The tests must be passed on application and the IELTS, TOEIC and TOEFL scores must be valid. Application There are 40 places available in the Master’s degree program in Molecular Biotechnology each year. The ratio of places to applicants is currently around 1:4.5.For organizational reasons, we recommend that applicants from outside the EU, EEA and Switzerland complete their application by end of February 2022 at the latest.To apply you will require the following documents:Letter of motivationCurriculum VitaeBirth certificate or equivalentPassport/proof of citizenshipBachelor's certificate/Diploma certificate/equivalent certificate from abroad/proof of matriculation3 4Transcript(s) of records4Written proof of your English skills (for applicants outside the EU, EEA and Switzerland)A completed table with the relevant ECTS credits from your previous studies: Biology (30, of which 20 are in biology theory and 10 are in biology labs/practical courses), Chemistry (15), Mathematics (6) - please click HERE to complete the table with relevant ECTS credits to open the file (PDF 1,1 MB)3 If you have not completed your studies at the time of application, please upload the current proof of matriculation and submit the graduation certificates on time.4 Please note the regulations for international certificates - click HERE (PDF 145 KB) for more informationPlease note: It is not possible to save incomplete online applications. You must complete your application in one session. Your online application will be accepted once you have uploaded all required documents. After completing your online application, you will receive an automatically generated reply e-mail with the application form. To consider your application as complete, please return the signed application form to biotechnologie@fh-campuswien.ac.at. Admission procedure If the application documents are fully provided and meet the admission requirements, you will be invited to participate in the first part of the admission procedure. The first part is a written admission test on the computer on site, where your knowledge of biology, molecular biology, cell biology, English, etc. on Life Science Bachelor’s level, as well as cognitive questions are tested.For the written admission test, which takes place at the main location of the FH Campus Wien, your personal presence in Vienna is required.After positive completion of the written admission test, you will be invited to the second part of the admission procedure, which is planned as an online interview. You will have the opportunity to present your motivation, your studies and your professional and scientific goals, as well as to answer knowledge questions at Life Science Bachelor’s level. The interview will be conducted with an online meeting tool.The test and the interview are scored and ranked.Criteria The criteria for acceptance are based solely on performance. The geographical origin of the applicant has no influence on the decision. The admission requirements must be met in all cases. Applicants are evaluated according to the following system: Written test 60%Interview 40%The committee, consisting of the head of the degree program and representatives of the teaching staff, awards places to the applicants who score highest in the admission procedure. The admission procedure as a whole, including tests and assessment results, are documented in a transparent and verifiable manner.Waiting list If you are not offered a place in the degree program but your score is considered good in comparison to others, you will be placed on the waiting list. This means that if another person declines their offer of a study place for the upcoming winter semester, applicants from the waiting list will be contacted. This can happen at short notice and no deadline can be determined in advance. You will be informed immediately if you are offered a spot in the degree program. Rejection by the degree program If you receive a rejection after the admission process, you can reapply for the next winter semester as soon as the application window is open again. You will then have to reapply online, submit all the necessary documents and go through the entire admission procedure again.Acceptance of the study place You will be informed via e-mail about the opportunity of receiving a place in the degree program. Attached to that you will find your training contract and a number of regulations. You need to return the signed contract in time (clearly stated in the e-mail) to secure and accept your place in the degree program. The accounting department will forward you the invoice for the tuition fee separately. This may take a few days. The timetable for the respective degree program is expected to be online one to two weeks BEFORE the beginning of each semester. All other study-relevant information will either be sent to you via e-mail, or you will receive it at the beginning of the academic year.Cancellation from the applicant’s side If you are unable or unwilling to accept your place in the degree program, please inform the Secretary's Office at biotechnologie@fh-campuswien.ac.at as soon as possible. Your place will then be allocated to the next person on the waiting list. Cancellations or withdrawal from the training contract will only be accepted in writing. Dates Application period: 1st January to 27th March 2022Written admission test: expectedly 25th-28th April 2022Online interview: expectedly 16th – 25th May 2022 Have you missed the Online-Infosessions? Do not worry, for those interested in studying, the videos are available to watch on YouTube.Watch now Studying with disabilities If you have any questions regarding accessibility or if you have a specific need in the admission procedure due to an impairment, please contact Ursula Weilenmann for organizational reasons as early as possible at barrierefrei@fh-campuswien.ac.at.Since we try to take into account individual needs due to disabilities when conducting the written admission test, we ask you to indicate in your online application to Weilenmann in which form you require support.Your contact person in the department Gender & Diversity ManagementMag.a Ursula Weilenmannbarrierefrei@fh-campuswien.ac.athttp://www.fh-campuswien.ac.at/barrierefrei Contact > FH-Prof. Mag. Dr. Beatrix Kuen-Krismer Head Department Applied Life Sciences, Head of Degree Program Molecular Biotechnology T: +43 1 606 68 77-3501bea.kuen@fh-campuswien.ac.at Secretary's office Elisabeth HablasVictoria Buchsbaum, MAVienna BioCenterHelmut-Qualtinger-Gasse 2, OG.A.011030 WienT: +43 1 606 68 77-3500 F: +43 1 606 68 77-3509biotechnologie@fh-campuswien.ac.atMap Vienna BioCenter (Google Maps)Office hours Mon to Fri, 8.00 a.m.-12.00 p.m. Information: Application and Admissionbiotechnologie@fh-campuswien.ac.atMag.a Janina Agis-BleiAssistanceVienna BioCenterHelmut-Qualtinger-Gasse 2, OG.A.031030 WienT: +43 1 606 68 77-3505F: +43 1 606 68 77-3509biotechnologie@fh-campuswien.ac.atNew study location from winter semester 2022/23 The Department of Applied Life Sciences will move to the new building at Favoritenstraße 222, 1100 Vienna in the summer of 2022. Teaching staff and research staff > FH-Prof. Dr. Thomas Czerny Academic Staff> FH- Prof. Mag. Dr. Marianne Raith Academic Staff> Dr. Elisabeth Riegel Academic Staff> FH-Prof. Univ.Doz. Dr. Ines Swoboda Head of Competence Center Molecular Biotechnolog, Academic Staff> Dr. Mary Grace Wallis Academic Staff> FH-Prof. Dr. Herbert Wank Academic Staff> FH-Prof. Dr. Paul Watson Academic Staff Cooperations and Campusnetzwerk We work closely with numerous biotech companies, universities, such as the University of Vienna, and research institutes and have a strong international network. This guarantees you strong contacts for a semester abroad, participation in research and development activities or your professional career. You can find information about our cooperation activities and much more at Campusnetzwerk. It's well worth visiting the site as it may direct you to a new job or interesting event held by our cooperation partners! Welcome to our Campusnetzwerk Find suitable job offers, build valuable mentoring relationships and expand your professional network - become part of our community!Register now for free Downloads Information Folder Molecular Biotechnology Master (PDF 122 KB)Folder Applied Life Sciences (PDF 831 KB)
1. Semesters LectureSWSECTSBioethics ILVBioethics ILVLector: Dr.in Mary Grace Wallis1SWS1ECTSLecture contentsCurrent (bio-)ethical topics relevant for the life sciences/pharmaceutical/biotech industry (see Learning Outcomes)Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, written group tasks, blended learning.LanguageEnglish11Bioinformatics ILVBioinformatics ILVLector: Mag. Dr. Walter Glaser2SWS2ECTSLecture contentsCommands in Linux Individual topics will be taken up and discussed in more detail, e.g: - biological sequences, sequence comparison - bioinformatic output formats/filesAssessment methodsContinuous assessment Continuous assessment including assessment of final projectTeaching methodsLectures, Powerpoint presentation, hands-on exercises and independent workLanguageEnglish22Clinical Drug Development ILVClinical Drug Development ILVLector: Dr. Astrid Christine Erber1SWS1ECTSLecture contents- Case studies: Clinical development of selected drugs (biopharmaceuticals and small-molecule drugs) - Classes of Pharmaceuticals - Clinical and epidemiological study designs - Outcomes and inclusion/exclusion criteria, special populations - Randomized Controlled Trials (RCTs): Randomization, Blinding and Placebos - Conduct of clinical trials - Data analysis and interpretation - Ethical aspects - The origins and principles of Good Clinical Practice (GCP) - International regulations (EMEA, FDA, ICH) - Interfaces: Regulatory Affairs and Pharmacovigilance, Marketing and Product Life Cycle Management - Special chapters: Generic drugs and biosimilars, orphan drugs and Advanced Therapy Medicinal ProductsAssessment methodsContinuous assessment Grading of participation and in-class exercises. Written exam at the end of the lecture course. Exam includes multiple choice questions as well as open questions.Teaching methodsLectures, small group discussions and in-class exercisesLanguageEnglish11General Pathology VOGeneral Pathology VOLector: Prim.Univ.Doz. Dr.med. Johann Feichtinger2SWS3ECTSLecture contentsStudents know and can explain the principles of general pathology, causes and development of pathological processes and diseases at the level of cells, tissues and the whole organism in detail. Students know and are able to describe the courses of illness and symptoms based on morphological alterations and clinicopathological correlations from the systemic/special pathology. In addition, students are familiar with and can explain the systematics and nomenclature of diseases as well as applied diagnostic and therapeutic strategies.Assessment methodsFinal exam Written multiple choice testTeaching methodsLecture (Powerpoint presentations, manuscript, glossary, mind maps) / Vorlesung (VL-Unterlagen als Powerpoint-Folien mit Schemata und Bildmaterial, VL-Manuskript, Glossar, Mind-Maps)LanguageEnglish23Intercultural Teams in Interdisciplinary Projects ILVIntercultural Teams in Interdisciplinary Projects ILVLector: Monika Frauwallner, DI Franz Gatterer, MBA, Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson1SWS1ECTSLecture contentsThe content of this integrated course, which is specially designed as the Kick-Off of the Master degree programme prepares the students from different countries, cultural backgrounds, universities, disciplines, and with individual life experiences to work together optimally in interdisciplinary, intercultural and international study and working environments. See the ‘Learning Outcomes' for further details.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, individual and group tasksLanguageEnglish11Medical Genetics VOMedical Genetics VOLector: Univ.-Prof.i.R. Dr. Christine Mannhalter2SWS2ECTSLecture contentsThe course will be divided in several parts: - summary of basic principles - discussion of molecular biological techniques including their limitations - discussion of several examples for genetic diseases, also in the context of useful and suitable methods (monogenetic, polygenetic, acquired). Students are encouraged to take the lead to preside over debates and scientific discussions on current scientific and/or ethical topics. At the end of the course, students undertake a quiz where they are encouraged to try to identify the cause of a disease.Assessment methodsFinal exam Preparation of a written manuscript to a specific topic, evaluation of the participation in discussions. (Seminar paper)Teaching methodsUse of Power Point presentation, regular discussions, use of quiz.LanguageEnglish22Medical Genetics Lab UEMedical Genetics Lab UELector: Ao.Univ.-Prof. Mag. Dr. Dietmar Abraham, Kay Holleis, BSc MSc, Andrea Krames, BSc MSc, Heidi Miedl, Ao.Univ.Prof. Dr. Martin Schreiber, Assoz.-Prof. Priv.-Doz. Mag. Dr. Karin Zins2SWS2ECTSLecture contentsVarious methods used in genetic analysis are explained and carried out practically. These include the reverse transcriptase polymerase chain reaction for the detection of leukemia associated fusion transcripts, gene amplification and hybridization to immobilized, allele specific oligonucleotides for the detection of mutations in the cystic fibrosis gene, and genotyping of a single nucleotide polymorphism (SNP) in a cohort of patients followed by statistical analysis of the association with disease risk.Assessment methodsContinuous assessment Immanent assessment of student's understanding of the subject, written laboratory report.Teaching methods- The theoretical basis of each of the analyses conducted in the laboratory is explained in a preceding seminar. - Students conduct genetic analyses according to detailed reports provided by the lecturers. - Laboratory results are discussed with lecturers at the end of each unit, and are summarized in a report whose structure corresponds to that of a scientific paper.LanguageEnglish22Molecular Genetics VOMolecular Genetics VOLector: FH-Prof. Dr. Thomas Czerny1.5SWS2ECTSLecture contents- Fundamental features of genetics and genetic engineering - Different levels of regulation of gene expression in pro- and eukaryotes - Transcriptional regulation (transcription in eukaryotes, transcriptional activation, properties of transcription factors) - Posttranscriptional regulation (splicing, transport, stability of mRNA, translational control) - Effects of chromatin (composition, histone modifications, regulation, epigenetics) - Examples from signalling pathwaysAssessment methodsFinal exam Written examsTeaching methodsLectures with Powerpoint presentationsLanguageEnglish1.52Molecular Immunology VOMolecular Immunology VOLector: Univ.Prof. Mag. Dr. Wilfried Ellmeier, Univ.Doz. Ao. Univ.Prof. Dr. Herbert Strobl2SWS3ECTSLecture contentsFundamental concepts of immunity, immunologic tolerance and autoimmunity, immunity to microbes, transplantation immunology, immunity to tumors, hypersensitivity disorders, allergy, congenital and acquired immunodeficiencies, immunotherapy and immunological methods.Assessment methodsFinal exam Written exam at the end of the lecture course. Exam includes multiple choice questions as well as open questions.Teaching methodsLectures, interactive discussions between students and lecturer.LanguageEnglish23Molecular Pathology VOMolecular Pathology VOLector: Ao. Univ. Prof. Mag. Dr. Wolfgang Mikulits, Ao. Univ. Prof. Mag. Dr. Ernst Müllner, Ao. Univ. Prof. Dr. DI Johannes Nimpf2SWS3ECTSLecture contentsIn this lecture course, initially the knowledge about the human genome is deepened. Building on that it is pointed out how genetic alterations can lead to disease. Further, methods to the identification of genetic diseases as well as methods for gene therapy are presented. The next part focuses on how aberrant molecular signal transduction can contribute to tumor development and metastasis. This is complemented by presentation of in vivo and in vitro tumor models. The final part is concerned with the topics of tissue printing and cell engineering. This is complemented by presenting novel developments in stem cell biology in normal as well as tumor tissues. Accompanying, in all parts important methods like flow cytometry, migration assays, fluorescence microscopy and blood cell analysis are addressed.Assessment methodsFinal exam Written exam after the end of the course; open questions, no multiple choice.Teaching methodsMainly powerpoint slides pointing out additional weblinks to literature sources, web-based texts and video content.LanguageEnglish23RNA VORNA VOLector: FH-Prof. Dr. Herbert Wank1SWS2ECTSLecture contentsRNA fundamentals, RNA structure, catalytic RNAs, RNA processing, RNA splicing, RNA editing, riboswitches, RNA applications, non-coding RNAs, RNAi, RNA world, SELEXAssessment methodsFinal exam Written exam at the end of the course.Teaching methodsLectureLanguageEnglish12RNA Analysis Lab VORNA Analysis Lab VOLector: Kay Holleis, BSc MSc, FH-Prof. Dr. Herbert Wank3SWS3ECTSLecture contentsRNA methods: - Northern blot (glucose/galactose metabolism in yeast, RNA extraction from yeast, denaturing RNA agarose gel, RNA transfer, specific oligonucleotide hybridization, band detection, quantitative PCR) - EMSA (in vitro transcription with T7 RNA polymerase, RNA purification, RNA folding, native polyacrylamide gel electrophoresis, RNA staining using methylene blue, detection of RNP complexes) - RNA stability (temperature dependence, pH dependence, RNAses)Assessment methodsContinuous assessment Continuous assessment - presence, motivation, participation, practical skills (results), written report.Teaching methodsLaboratoryLanguageEnglish33Scientific Communication I ILVScientific Communication I ILVLector: Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson2SWS3ECTSLecture contentsThe scientific and ethical content (see the ‘Learning Outcomes' for specific details) of this course aligns with the aims of the Master degree programme, and by working closely with other lecturers compliments the content of the other courses.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, discussions, written individual and group tasks, blended learning.LanguageEnglish23Vascular Biology VOVascular Biology VOLector: Ass.Prof. MMag. Dr. rer. nat. Alice Assinger1SWS2ECTSLecture contentsStudents are able to decribe the three main areas: hematology, vascular biology and vascular pathology. Hematology deals with the following topics: 1. erythrocytes (structure, cytoskeleton, hemoglobin, gas exchange, erythrocyte breakdown, iron metabolism, blood groups) 2. leukocytes (morphological leukocyte differentiation) 3. Platelets (structure, activation, adhesion, aggregation, interaction with cells or with the extracellular matrix) 4. Hemostasis (plasmatic coagulation, cell-based model of coagulation, fibrinolytic system, inhibitor systems, blood coagulation tests) 5. Laboratory diagnosis of blood (sample collection, plasma/serum, sample composition/sources of error, clinical chemistry, red/white blood count, blood group serology) 6. Hematological diseases (reactive changes of the erythrocytes/leucocytes/platelets, disorders of hemostasis) / Vascular biology deals with: 1. an overview of the vascular system (terms, structure, blood vessel system / lymphatic system) 2. development of the blood vessels (vasculogenesis, angiogenesis, significance and function of specific angiogenic growth factors) 3. the endothelium (biology of the endothelial cell, structure of endothelia, endothelial species) 4. the functions of the endothelium (regulation of vascular tone, endothelium and cell adhesion, endothelial dysfunction) Vascular pathology describes: 1. the role of the endothelium in the acute inflammatory response (systemically explained by the example of sepsis and locally using the example of "acute lung injury" and 2. atherosclerosis described as a chronic inflammatory vascular disease (risk factors, lipid metabolism, atherogenesis, pathophysiology of unstable plaque / plaque rupture, animal models in atherosclerosis research).Assessment methodsFinal exam Exam; single-choice questions and essay about a topic.Teaching methodsReading of primary literature, lectures with power point and flip chart, self-study.LanguageEnglish12
2. Semesters LectureSWSECTSBiologicals VOBiologicals VOLector: Dr. Klaus Rumpel1SWS1ECTSLecture contentsThe lecture course "Biologicals" gives an overview over the most important aspects of biotherapeutics (= biologics) which is the fastest growing type of drug gaining more and more importance. The focus of the course is the discovery research of therapeutic concepts enabled by engineering of biologics, bioprocess development of biologicals, and manufacturing aspects. Major differences and therapeutic aspects differing between small molecule drugs and biologics are discussed; examples of major classes of biologics are presented as case studies. Discovery and engineering of therapeutic monoclonal antibodies are discussed in more detail as this class of therapeutics reflects the biggest class amongst many other biologicals. Approaches and technologies for biopharmaceutical manufacturing and purification will be discussed; major aspects and challenges of protein analytics and physicochemical characterization of biologics will be highlighted.Assessment methodsFinal exam Written exam in the last lectureTeaching methodsLectureLanguageEnglish11Drug Screening VODrug Screening VOLector: Michael Nagl, Dr, Prof.(FH) Mag. Dr. Christoph Wiesner1SWS1ECTSLecture contentsStudents learn how to isolate natural drugs (small molecules) from plants or how to produce biologics. Course content also includes different in vitro screening methods, HCS, HTS (including target-and phenotype-based drug discovery).Assessment methodsFinal exam Final written exam (100%)Teaching methodsLectureLanguageEnglish11In Silico Biology VOIn Silico Biology VOLector: Mag. Dr. Walter Glaser3SWS3ECTSLecture contentsBioinformatics topics will be addressed and the practical solution of biological problems with bioinformatics tools will be discussed. The topics include: - the Human Genome (Genome analysis: SNPs, Variant Discovery) - biological batabases - data formats - protein domains, regulatory patterns - non-coding RNA prediction - gene set analysisAssessment methodsFinal exam Written test on the theoretical part (50%), report (50%)Teaching methodsLectures, Powerpoint presentation, discussion and independent hands-on exercises with bioinformatics toolsLanguageEnglish33Infection Biology VOInfection Biology VOLector: Priv. Doz. Dr. rer. nat. habil. Holger Scholz, Professor und Direktor, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda2SWS2ECTSLecture contentsIn this lecture, beside the basics of medical microbiology, the complex interactions between pathogens and the human host are presented and the molecular, cellular and immunological aspects of this interaction are explained. Strategies developed by bacteria, viruses, fungi and parasites to colonize, invade, survive, reproduce and spread are discussed. Furthermore, the cellular and systemic effects on the host, the host's defence mechanisms and the clinical manifestations of the infectious diseases are shown. In addition, principles of the diagnosis of infectious diseases as well as antimicrobial and antiviral treatment options are explained and concepts behind the development of novel diagnostic tools, drugs and vaccines for future prevention and therapy of infectious diseases are presented. The lecture is rounded off by a detailed presentation of selected infectious diseases using clear visual material and a presentation of own research activities.Assessment methodsFinal exam Written exam in the end of the lecture courseTeaching methodsLectureLanguageEnglish22Innovation in Biotechnology & Start-Ups ILVInnovation in Biotechnology & Start-Ups ILVLector: DI Franz Gatterer, MBA2SWS2ECTSLecture contentsDefinitions and meaning of Knowledge and the management of knowledge in a knowledge-driven society in general and in the field of Biotechnology in particular with heavy focus on phases of Research and Development (R&D). What is it? Definitions? Perspectives: The human and the data, principles, types, processes, concepts, tools and practice. From Invention (Research/Technology) to Innovation: The Management of Innovation. Definitions and basics, the process of Innovation Management, the strategic dimension of innovation. Innovation analyses/assessment and organisational aspects of implementation. From a business idea to a business plan: The story of a business plan and its elements (externally and internally). The business idea, the vision/mission statement and it's reflection in a certain product/service, the targeted market with its characteristics (such as customers, competitors, partners, etc.), the financials, the legal environment, the organisation needed to drive business implementation, the plan for implementation. The four phases for business-plan development and its implementation: Build hypotheses derived from a business idea, feedback, maturing it through “friendly customers”, incorporate results and show business plan to real customers, to real investors (or funding organisations), if successful, go through foundation process, business start and ongoing improvements. Useful Tools: Porter Model – 5 Forces, SWOT Analyses; Life-Cycle Analyses; Canvas Business Model Concept, BP-Calculation templates, BP templates; Risk Analyses.Assessment methodsFinal exam Evaluation of group results (a complete business-plan plus a BP presentation). In addition, individual interviews with students about their results facilitates quality assurance respectively control at an individual level. (Group work)Teaching methodsStudent-centred methods: project work in fixed groups, presentations, partly: flipped class-room approach, debates, discussions, written tasks.LanguageEnglish22Intellectual Property & Patent Law VOIntellectual Property & Patent Law VOLector: Dr. Irene Fialka, CMC, Mag. Dr. Manuela Loidl1SWS1ECTSLecture contents• Which forms of protection of intellectual property are available? – trademark, industrial design, copyright, utility model, complementary protection certificate, patent • History of patent rights • What is a patent? – effects of a patent – what can be patented and what is excluded from patent protection? – what are the prerequisites for patent application/protection? – How to define an inventor? Rights and obligations of employee inventors • From application to patent grant – structure of a patent application – application and granting processes - protective reach and duration – legal measures – fees and costs – where to apply for a patent • Rights of patent owners and legal measures • International agreements (EP, PCT), important national differences • Biopatents – legal framework, important decisions • Freedom to Operate • Espacenet and how to use it for patent research • Patent lawyer - the profession • Fundamentals in copyright • Fundamentals in industrial design • Fundamentals in trademark • Strategies and decision making • Important agreements– MTAs, CDAs, licensing contracts • Licensing contracts - fundamental principles, important clauses – FranchiseAssessment methodsContinuous assessment Written exam at the end of the course.Teaching methodsLectures with interactive elements and discussions, actual cases will be discussed in more detail.LanguageEnglish11Molecular Pathology Lab UEMolecular Pathology Lab UELector: Kristina Breitenecker, MSc, Ao. Univ. Prof. Mag. Dr. Wolfgang Mikulits, Ao. Univ. Prof. Mag. Dr. Ernst Müllner3SWS3ECTSLecture contents- Various tissue staining techniques; patho-histological evaluation of tumor tissue samples and photographical documentation; characterization of blood by flow cytometry; determination of leucocytes in blood smears; blood sugar measurements in oral glucose-tolerance tests - Isolation of chicken granulosa cells from pre-ovulatory follicles; fluorescence microscopy of thin sections of follicles; stimulation of transgenic fibroblasts (ApoER2+Dab1 or VLDLR+Dab1) with Reelin followed by detection of Dab1 phosphorylation by immunoprecipitation and Western blotting - Proliferation kinetics and clonogenic assays; cell migration and wound healing assays; cell migration assays using transwellsAssessment methodsContinuous assessment Immanenter Prüfungscharakter durch permanente Beobachtung der Mitarbeit und des persönlichen Engagements; Qualität der Datenauswertung und Dokumentation im schriftlichen ProtokollTeaching methodsPractical laboratory course accompanied by introductory seminarsLanguageEnglish33Molecular Virology VOMolecular Virology VOLector: Ao.Univ.Prof. Dr. Dieter Klein, Dr.rer.nat. Christoph Metzner1SWS2ECTSLecture contentsReplication cycle of important virus families, pathogenetic mechanisms of important viruses, anti-viral strategies, and importance of viruses in molecular biology and medicine.Assessment methodsFinal exam Written examinationTeaching methodsInteractive LectureLanguageEnglish12Scientific Communication II ILVScientific Communication II ILVLector: Dr.in Mary Grace Wallis, FH-Prof. Dr. Paul Watson2SWS2ECTSLecture contentsThe scientific and ethical content (see the ‘Learning Outcomes' for specific details) of this course aligns with the aims of the Master degree programme, and by working closely with other lecturers compliments the content of the other courses.Assessment methodsContinuous assessment Continuous assessmentTeaching methodsStudent-centred methods: presentations, debates, discussions, written individual and group tasks, blended learning.LanguageEnglish22Signalling Pathways VOSignalling Pathways VOLector: FH-Prof. Dr. Thomas Czerny1SWS2ECTSLecture contentsImportant signalling pathways of the cell (e.g. MAP kinase-, GPCR-, Nuclear Hormone Receptor-, NF-kB-, Jak/Stat-, Wnt-, Hedgehog-, Tgfß-, Apoptosis-, PI3K/Akt- and stress pathways) are presented together with their effects on gene expression and other functions of the cell. In addition the crosslinks with other pathways are discussed. Techniques for the analysis of signalling pathways are also presented.Assessment methodsFinal exam Written ExamTeaching methodsLectures with Powerpoint presentations, Discussion of selected chaptersLanguageEnglish12Signalling Pathways Lab UESignalling Pathways Lab UELector: Andrea Krames, BSc MSc, Dr.in Elisabeth Riegel3SWS3ECTSLecture contentsMethods for the manipulation and the analysis of signalling pathways in cell culture are applied, broadening the knowledge on specific pathways. The applied methods are transient transfection in cell culture, reporter constructs with gfp and luciferase, overexpression of activators/repressors (including RNAi), Western analysis of cellular extracts, analysis of phosphorylation, fluorescence microscopy of labelled proteins and pharmacologic manipulation of the pathways.Assessment methodsFinal exam Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experiments. (Seminar paper)Teaching methodsLaboratory workLanguageEnglish33Stem Cells VOStem Cells VOLector: Dr. Arabella Meixner1.5SWS2ECTSLecture contentsReports about stem cells and their usage in biomedical research has raised several important key questions about their capacity to use for stem cell-based therapies to cure diseases. Our course starts with an overview about stem cell biology, where to find stem cell and might there be a different o stem cells isolated from various organisms, such as axolotl. We start to understand how an organsims is developing and where to find stem cells in a human body. For a deeper knowledge in stem cell biology we learn about induced pluripotent stem cells and the development of mini organs/organoids. We discuss the potential usage of stem cells in clinical applications, the importance for society and relevant ethical aspects. Finally, we present latest key news and views about recently published stem cell research breakthroughs.Assessment methodsFinal exam Written examTeaching methodsInteractive lectures with discussions using Power point presentation and the blackboardLanguageEnglish1.52Stem Cells Lab UEStem Cells Lab UELector: Mag. Dr. Thomas Dechat, Nina Malajner, MSc, Dr. Arabella Meixner2.5SWS3ECTSLecture contentsThe course teaches the fundamentals of the culture of murine embryonic stem cells and induced stem cells and practical applications. Different cultivation possibilities for ESC and the control of the stability of the cultures in the undifferentiated state will be learned (morphological analysis, alkaline phosphatase assay). Targeted differentiation using the embryoid body (EB) model will be learnt and in addition, experimental investigations will be carried out on how different inhibitors or activators influence differentiation. The formation of EB is analyzed by light microscopy. Using an example, the use of CRISPR/Cas in stem cells will be practiced.Assessment methodsContinuous assessment Continuous assessment. The grade is comprised of the following sections: attendance, motivation, cooperation, written reportTeaching methodsPractical laboratory courseLanguageEnglish2.53 Electives 1 (1 ECTS of your choice)LectureSWSECTSDrug Discovery SEDrug Discovery SELector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of Drug Discovery are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsFinal exam Participation in discussion (Seminar paper)Teaching methodsSeminarLanguageEnglish11Molecular Immunology SEMolecular Immunology SELector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of Molecular Immunology are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsContinuous assessment Participation in discussion (Seminar paper)Teaching methodsSeminarLanguageEnglish11RNA SERNA SELector: FH-Prof. Dr. Herbert Wank1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of RNA research are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsContinuous assessment Participation in discussionTeaching methodsSeminarLanguageEnglish11 Electives 2 (2 ECTS of your choice)LectureSWSECTSTherapeutic Strategies VOTherapeutic Strategies VOLector: Doz. Mag. Dr. Wolfgang Sommergruber1SWS2ECTSLecture contentsTherapeutic strategies based on signal transduction pathways in health and disease provides a detailed view of the underlying molecular biology of selected diseases and novel treatment modalities with a particular focus on oncology. Clinical failures and validity of targets, Extracellular signaling (endocrine – paracrine – autocrine; Multitype) - Mechanisms of signal transduction and the determination of the fate of a cell - Intracellular signal-transduction (signaling by phosphorylation and GTP-binding) - PD-1/PD-L1 and CTLA-4 signaling in immune cells - Molecular mechanisms of EMT - Ligand-binding and effector specificity of receptor proteins - Acetylcholine: Same signal can lead to different effects in cells of different tissues - Hormones: Small lipophilic molecules and their intracellular receptors; hydrophilic and lipophilic hormones and their cell-surface receptors - Hormone receptors (retinoid-x-receptor; PR, GR, AR and ER receptors) - Hashimoto's thyroiditis, Graves' disease - Nuclear receptors - Prostaglandin (PG) Biosynthesis (COX1, 2; COX inhibitors) - Prostaglandin signal-transduction pathways - Insect and snake venom (PLA2) - Prostaglandins in breast cancer and endometriosis (autocrine and paracrine actions of PEG2 and PEF2a - Biphasic activation of FGF-9 by PGE2 - Phagocytic ability of macrophages and PEG2 - StAR aromatase and aromatase inhibitors - G protein-coupled receptors - Ion-channel receptors - Tyrosine kinase-linked receptors - Receptors with intrinsic enzymatic activity - EGFR (mechanisms of EGFR dysregulation - Therapeutic concepts, types of biomarkers - Molecular mechanisms of oncogene addiction and clinical resistance - Compensatory pathways in oncogenic kinase signaling and resistance to targeted therapies (EGFR, BRAF, SMO) - Dual-specificity phosphatases: Critical regulators with diverse cellular targets - The hedgehog and Hippo pathway in development and disease - Fusion proteins of ALK and their contribution to tumorigenesis - Tyrosine kinase-linked receptors - Mechanisms to die: Immunogenic cell death (ICD).Assessment methodsFinal exam Written exam and a short oral presentation (5 minutes, FlipChart) + feedbackTeaching methodsOral presentations with PowerPoint slides, printed handouts will be provided (if requested), short presentations by students on selected topics (FlipChart); see also Assessment Methods.LanguageEnglish12Vaccine Development VOVaccine Development VOLector: Dr. Shailesh Dewasthaly1SWS2ECTSLecture contentsStudents know and can explain the currently used vaccines and the approaches to the development of vaccines against known and emerging infectious diseases. Furthermore, students can describe how the vaccines are being developed from an ‘industrial perspective' and can appreciate the complexities involved in development of vaccines all the way to licensure of the vaccines. Post licensure effectiveness of the vaccines are also discussed. Students gain a deeper understanding of the development and production of vaccines from the laboratory to the clinical trials by carrying out independent literature research and communicating their findings with supporting media (peer teaching), using current globally significant vaccines as examples.Assessment methodsContinuous assessment Continuous assessment, assignment and presentationTeaching methodsInteractive lectures with Powerpoint slides and active participationLanguageEnglish12
3. Semesters LectureSWSECTSAllergies & Autoimmune Diseases VOAllergies & Autoimmune Diseases VOLector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS2ECTSLecture contentsIn this lecture course the molecular and cellular mechanisms of allergies and other hypersensitivity reactions are explained and the symptoms, causes and risk factors of allergic diseases are described. Furthermore, advantages and disadvantages of current diagnostic tests and therapeutic possibilities are discussed and strategies for improvement of diagnosis and therapies of allergies are introduced. This lecture course also explains the pathomechanisms underlying autoimmune disorders and describes determinants (such as genetic predisposition or environmental factors) that influence the development autoimmunity. In addition, the pathogenesis, clinical manifestation and the treatment possibilities of a few selected autoimmune diseases (e.g., Rheumatoid Arthritis, Multiple Sclerosis) are discussed. Furthermore, this lecture course also highlights similarities and differences between allergies and autoimmune disorders.Assessment methodsFinal exam Written exam after the last lectureTeaching methodsLectureLanguageEnglish12Computational Data Analysis ILVComputational Data Analysis ILVLector: Mag. Dr. Walter Glaser2SWS2ECTSLecture contents1) Acquire knowledge on selected bioinformatics chapters (Next Generation Sequencing, ChIP-Seq, RNA-Seq), and 2) Application of relevant bioinformatics tools to analyse the associated data.Assessment methodsFinal exam 100 % Report in which students have to analyse RNA-Seq Data/ChIP-Seq DataTeaching methodsIntroductions and explanations (lecture), Exercises using the computerLanguageEnglish22Drug Design VODrug Design VOLector: Dr. Klaus Rumpel2SWS2ECTSLecture contentsAt the center of this course is the drug and its interaction with target proteins. Methods for determination of protein structures and characterization and quantification of protein ligand interactions are presented. In addition strategies and methods for the optimization of these interactions are discussed (lead optimization, rational design). Furthermore, aspects of pharmacokinetics (ADME, prodrugs) are presented. The underlying principles are demonstrated by selected examples.Assessment methodsFinal exam Written exam in the last lectureTeaching methodsLectures (Powerpoint presentations and downloads)LanguageEnglish22Gene Therapy VOGene Therapy VOLector: Ao.Univ.Prof. Dr. Dieter Klein, Dr.rer.nat. Christoph Metzner1SWS2ECTSLecture contentsPrinciples of gene therapy, overview on applications of gene therapy, gene transfer methods, methods for gene transfer estimation, characteristics of different viral vector systems, non-viral vector systems, lenti-/retroviral vectors, adenoviral vectors, adeno-associated viral vectors, applications of gene therapy for different diseases, problems and perspectives.Assessment methodsFinal exam Written examinationTeaching methodsInteractive lectureLanguageGerman12Mass Spectrometry ILVMass Spectrometry ILVLector: Claudia Ctortecka, MSc, DI Dr. Johannes Stadlmann2SWS2ECTSLecture contentsDuring the "hands on" laboratory every student excises a band containg a protein out of a 4-20% SDS-PAGE (Tris/Glycine) gradient gel. Purification, reduction and alkylation of Cysteines, o/n digestion with Trypsin, next day spotting onto a MALDI target, and generation of a PMF mass spectrum with MALDI-TOF and MSMS spectra of the most intense peptides. Subsequently identification of the protein with database search algorithms. The theoretical part provides an introduction into the basic principles of proteomics: sample preparation & fractionation (1D and 2D GE, HPLC, CE, SCX RP and affinity chromatography, difficulty of contamination e.g. keratins, SDS, salts). Explanation of the principles of mass spectrometry: ion sources (MALDI, ESI), types of mass spectrometers (TOF, quadrupole, ion trap, FT ICR) and the respective combinations e.g. MALDI-TOF/TOF etc. Resolution R and mass accuracy dm/m (ppm). Improvement of the latter by delayed extraction & reflectron for MALDI-TOF. Isotopic distribution, single and multiple charged ions (ESI). PMF (peptide mass fingerprinting), principles of data base analysis of mass spectra. Collision induced dissociation CID, MS/MS analysis and de novo sequencing. In addition, an introduction into the methods of quantitative proteomics as well as the analysis of post-translational modifications will be included, as well as an introduction into the application of mass spectrometry (and other technologies) to further analytical questions in addition to proteomics, e.g. metabolomics, lipidomics, drug development and environmental research. Finally, students present an exposé with their own concepts how to tackle a specific analytical question, using the methodology discussed in the course.Assessment methodsContinuous assessment Active course participation, results of written test and/or oral examination, evaluation of laboratory report and exposé on potential research project using mass spectrometryTeaching methodsWet laboratory work, tutorial on all theoretical contents, video material, data analysis on computer, critical evaluation of data.LanguageEnglish22Master Project Seminar ILVMaster Project Seminar ILVLector: FH-Prof. Mag. Dr. Beatrix Kuen-Krismer1SWS1ECTSLecture contentsDuring this course, the students independently - with the support of the Master's Thesis Coordinator - seek a research project in an inter/national life science research institution or research company, whose content, quality and duration is suitable to write a high-quality master's thesis. Together with the direct supervisor of the research project, the students prepare a project plan for the course of the research project. The plan contains the project goals, the problem definition and the method spectrum to be used. In small groups, the students present the elaborated plans of their planned research projects to their peer group as well as their motivation to carry out this research project. The group discusses and reflects on the presented problems, strategies and methods and gives their feedback.Assessment methodsContinuous assessmentTeaching methodsActivating Methods: e.g. presentations, discussions …LanguageEnglish11Molecular Immunology Lab UEMolecular Immunology Lab UELector: Kay Holleis, BSc MSc, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda3SWS3ECTSLecture contentsIn the Molecular Immunology laboratory the theoretical immunological knowledge is deepened and practically applied to research problems from the field of allergy research. Students work in small groups of 2 to 3 people on a scientific research question. As a team they have to find the best way to answer the research question, they have to design and perform the experiments using state-of-the-art immunological and molecular biological methods such as ELISAs, SDS-PAGE, immunoblotting, PCR, microscopy and flow cytometry. Finally, each student writes a laboratory report in the format of a scientific publication, in which the background of the research topic is summarized and the experimental work, the results and the conclusion are described.Assessment methodsContinuous assessment Continuous assessment, active participation, reportTeaching methodsLaboratoryLanguageEnglish33Molecular Neurobiology VOMolecular Neurobiology VOLector: Dr.phil. Dr. med.univ. Karl-Heinz Huemer2SWS3ECTSLecture contentsStudents are able to explain membrane physiology, the development of action potentials, electrotonic and saltatoric conduction, synapses, important transmitters and the resulting pharmacological modulation, temporal and spatial integration, pre- and postsynaptic inhibition, as well as, motor functions of the spinal cord, basal ganglia, cerebellum, and cortex including disorders caused by lesions in these regions, the structure and function of the autonomic nervous system including effects on important organs, and the function of the sensory systems.Assessment methodsFinal exam Written examTeaching methodsLectureLanguageEnglish23Molecular Pharmacology ILVMolecular Pharmacology ILVLector: Mag. Dr. Gerda Brunhofer-Bolzer, MSc.2SWS3ECTSLecture contentsStructure and function of drug targets on the molecular level as well as their role as regulators of cell function, the prodrug strategy, and most frequently prescribed drugs for the treatment of human diseases (e.g. background of a disease, mechanism of action, important side effects).Assessment methodsFinal exam Written examination at the end of the course, evaluation of the tasks provided during the courseTeaching methodsEach topic is introduced and necessary information is provided through didactic lectures and e-learning methods. Subsequent lectures focus on the use of this information (e.g. discussion of research papers or research problems, student/poster presentations).LanguageEnglish23Strategic Business Management ILVStrategic Business Management ILVLector: DI Franz Gatterer, MBA2SWS2ECTSLecture contentsThe Strategic Business Management course is built on four pillars. I) Leadership and Management of enterprises/projects for Industry and/or Academia The major drivers for modern business management are addressed (innovation, globalisation, market dynamic, etc.). From there, the difference of management and leadership will be explained. Build on fundamentals of systemic thinking, reflected for the background of complexity, innovation and change, the differences of working “on a system” (leadership) and working “in a system” (management) will be explained and discussed. Pros/Cons will be elaborated for different environments. The different traditional management styles will be enhanced by leadership approaches and mapped to leading people (individuals) and organisations (teams) in a dynamic branch. II) Strategic Thinking – Strategy Development (Strategic Concepts – from Vision/Mission to Strategy) and its Elements in a Holistic Approach A company's identity through vision, mission and corporate culture as framework for its strategy is the baseline of this chapter. A vision and its important function for organisations and its individuals as initial impulse for orientation and order, as success driving function for alignment and motivation will be explored. The effectiveness of visions in the sense of positioning, top down implementation, targets and continuous communication is analysed. The Porter Model is explained and used to show different strategy types (e.g. product market Strategies (Ansoff), competitive strategies, development strategies). III) The Operational Perspective of Business Management – Strategy Implementation (Management-system, Framework and Indicators) The importance, characteristics and elements of management systems are explained and elaborated by analysing different models such as Balanced Scorecard, EFQM Model and/or ISO 9001:2015. It is shown, how a set of policies, processes and its alignment to the organization is targeted to achieve company´s objectives. IV) Adopted Company – A capstone project, where students apply the learning outcomes by analysing all elements learned in I-III The strategic analysis of a selected, “adopted” company builds the final capstone of the lecture course. Students analyse all relevant elements of a company (vision, mission, values/culture, strategic approach and goals related research, product portfolio, human resources, market, sales, etc.) and derive strategic recommendations for the company to successfully mature its market position. The entire course content will be critically addressed by future requirements as well as trends and developments in biotechnology business areas.Assessment methodsContinuous assessment Evaluation of group results (results of “adopted company” analyses and suggestions). In addition, individual interviews with students about their results facilitates quality assurance respectively control at an individual level.Teaching methodsStudent-centered methods: project work in fixed groups, presentations, partly: flipped class-room approach, debates, discussions, written tasksLanguageEnglish22Toxicology Lab UEToxicology Lab UELector: Kay Holleis, BSc MSc, Dr.in Elisabeth Riegel3SWS3ECTSLecture contentsThe toxicological and therapeutic potential of a small molecule drug will be estimated with a variety of cell based test systems. On the one hand the activating potential of the small molecule on a specific pathway (heat shock response pathway) is analysed and on the other hand possible cytotoxic effects are estimated in a concentration-dependent manner. A broad variety of assays is provided for the students including luciferase reporter assays, Western blot, qPCR, flow cytometry, ELISA and general viability assays. The students themselves select suitable methods.Assessment methodsContinuous assessment Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experimentsTeaching methodsPractical course with independent performance of the experiments.LanguageEnglish33Tumour Biology VOTumour Biology VOLector: Ao. Univ. Prof. Mag. Dr. Jozefa Gadek-Wesierski2SWS3ECTSLecture contentsThis course offers an overview of the changes and disturbances of the correct regulation of the cell cycle progression and of the dysfunction of the induction and execution of the programmed cell death and metabolism which occur during the malignant transformation and finally lead to cancer development. Moreover, it includes the description of the most important post-translational modifications of proteins and their role in the functional regulation of distinct proteins involved in the signal transduction. It gives an understanding of the expression and the function of tumour suppressor genes and proto-oncogenes as well as the changes of their regulation (inhibition or constitutive activation) that essentially contribute to cancer development. This course aims at giving students an overall view of the complexity of the carcinogenesis that encompasses cooperation between a variety of changes, dysfunctions and pathways. This course includes several topics depicting the involvement of genetic and external factors in carcinogenesis. It also gives an understanding of the role and balance between distinct suppressors and oncogenes in angiogenesis and metastasis.Assessment methodsFinal exam Evaluation of regular participation and active cooperation as well as final written examinationTeaching methodsEvaluation of regular participation and active cooperation as well as final written examinationLanguageEnglish23 Electives 3 (1 ECTS of your choice)LectureSWSECTSComputer-Assisted Systems & Data Integrity ILVComputer-Assisted Systems & Data Integrity ILVLector: DI Dr. Timo Kretzschmar1SWS1ECTSLecture contentsIntroduction to the fundamentals of validation and operation of computerised systems in the pharmaceutical industry and regulative environment as required to be compliant with the current EU regulations • GxP requirements to be considered • Quality risk management • Qualification / validation of systems ... • Management of deviations and changes • Corrective and preventive actions • Appropriate documentation • Navigation in a multivalent working environment • Typical systems as examples, introduced from the systemic point of view (ERP, MES, diverse databases, LIMS, cloud systems, data storage and retention systems and procedures like electronic archiving and backup procedures) • Practical examples as the core of explanations applied to the legislative demandsAssessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsLectures combined with discussion, based on practical examplesLanguageEnglish11Regulatory Affairs & Pharmacovigilance ILVRegulatory Affairs & Pharmacovigilance ILVLector: Mag.rer.nat Sabina Benes, Mag.pharm. Dr. Regina Lauer1SWS1ECTSLecture contentsRegulatory affairs, the main contact point to health authorities and, pharmacovigilance, patient safety post clinical development, see Learning Outcomes for specific details.Assessment methodsContinuous assessmentTeaching methodsInteractive lectures with discussionsLanguageEnglish11 Electives 4 (1 ECTS of your choice)LectureSWSECTSScientific Method: Drug Discovery SEScientific Method: Drug Discovery SELector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel1SWS1ECTSLecture contentsIn this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Drug Discovery), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency, Finally each group presents its research project.Assessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsSeminarLanguageEnglish11Scientific Method: Immunology SEScientific Method: Immunology SELector: FH- Prof.in Mag.a Dr.in Marianne Raith, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Immunology), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency. Finally each group presents its research project.Assessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsSeminarLanguageEnglish11
4. Semesters LectureSWSECTSMaster Exam APMaster Exam AP0SWS2ECTSLecture contentsThe Master's examination represents the final examination of the Master's program before an examination committee of experts. The students present their Master's thesis in the form of a lecture. The students are questioned about their presentation and they defend the contents and conclusions of their Master's thesis. They are asked to cross-connect the topic of their Master's thesis to relevant subjects of the degree program. The students reflect and discuss current research topics from the main fields of the Master's program with the examination committee of experts.Assessment methodsFinal exam For the presentation of the Master's thesis up to 40 points are awarded by the examination committee. Up to 30 points are awarded for the subsequent discussion on the presentation. Up to 30 points are also awarded for the discussion of current research topics from the main areas of the Master's program. The sum of these points gives the overall grade for the Master's examination.Teaching methodsActivating Methods: presentations and oral examLanguageEnglish02Master Thesis MTMaster Thesis MT0SWS28ECTSLecture contentsWriting an English language Master‘s thesis.Assessment methodsFinal exam Assessment by experts.Teaching methodsLaboratory and literature researchLanguageEnglish028
Admission requirements Bachelor’s certificate, Diploma certificate or equivalent certificate from abroad Bachelor’s degree or equivalent similar qualification from an institute of higher education with a total of 180 ECTS credits in the disciplines of molecular biology, biology with a focus on genetics and/or microbiology, biotechnology, pharmacy, medicine, food biotechnology or biomedical sciences with at least: 30 ECTS credits in Biology, where at least 20 ECTS credits must be in molecular biology, genetics, cell biology, microbiology, genomics and/or biotechnology and at least 10 of these ECTS credits must be in biological labs/practical courses during the degree program, 15 ECTS credits in chemistry (general, analytical, physical, organic, bioorganic, biochemistry), and 6 ECTS credits in mathematics, statistics, informatics. In order to assess whether you have the required ECTS credits for the Master’s degree program Molecular Biotechnology, please complete the linked table, also add existing or missing credits as part of the application - please click HERE to fill out the table to open the file (PDF 1,1 MB)If the applicant graduated from an education system, which does not use the ECTS credit system, it is the applicant’s responsibility to demonstrate ECTS-equivalence.If you meet the admission requirements and if the ECTS credits are only slightly below the required number, it will be decided on a case-by-case basis whether the additional ECTS credits can be compensated by additional examinations in order to allow admission to the degree program.Equivalent certificate from abroad - Equivalence is determined by international agreements, validation or in individual cases a decision by the head of the academic section.Information for applicants with non-Austrian (school) certificates (PDF 145 KB)Regulation for the admission of third country citizens (PDF 233 KB)English language proficiency at CEFR level C1The program is conducted entirely in EnglishStudents who have obtained their higher education entrance qualification and Bachelor's degree in the EU, EEA or Switzerland do not require proof of their English language skills.Students who speak English as their first language must prove their nationality, place of birth and length of stay in a country with English as their official language.All other students must provide written proof of their English proficiency, e.g. by a currently valid certification of one of the following tests: Test of English for International Communication (IELTS) 7-9Cambridge English Advanced (CAE)Cambridge English Proficiency (CPE)Test of English for International Communication (TOEIC) 880-990Test of English as a Foreign Language, internet-based test (TOEFLiBT ) 110-120UNICERT (III) The tests must be passed on application and the IELTS, TOEIC and TOEFL scores must be valid.
Application There are 40 places available in the Master’s degree program in Molecular Biotechnology each year. The ratio of places to applicants is currently around 1:4.5.For organizational reasons, we recommend that applicants from outside the EU, EEA and Switzerland complete their application by end of February 2022 at the latest.To apply you will require the following documents:Letter of motivationCurriculum VitaeBirth certificate or equivalentPassport/proof of citizenshipBachelor's certificate/Diploma certificate/equivalent certificate from abroad/proof of matriculation3 4Transcript(s) of records4Written proof of your English skills (for applicants outside the EU, EEA and Switzerland)A completed table with the relevant ECTS credits from your previous studies: Biology (30, of which 20 are in biology theory and 10 are in biology labs/practical courses), Chemistry (15), Mathematics (6) - please click HERE to complete the table with relevant ECTS credits to open the file (PDF 1,1 MB)3 If you have not completed your studies at the time of application, please upload the current proof of matriculation and submit the graduation certificates on time.4 Please note the regulations for international certificates - click HERE (PDF 145 KB) for more informationPlease note: It is not possible to save incomplete online applications. You must complete your application in one session. Your online application will be accepted once you have uploaded all required documents. After completing your online application, you will receive an automatically generated reply e-mail with the application form. To consider your application as complete, please return the signed application form to biotechnologie@fh-campuswien.ac.at.
Admission procedure If the application documents are fully provided and meet the admission requirements, you will be invited to participate in the first part of the admission procedure. The first part is a written admission test on the computer on site, where your knowledge of biology, molecular biology, cell biology, English, etc. on Life Science Bachelor’s level, as well as cognitive questions are tested.For the written admission test, which takes place at the main location of the FH Campus Wien, your personal presence in Vienna is required.After positive completion of the written admission test, you will be invited to the second part of the admission procedure, which is planned as an online interview. You will have the opportunity to present your motivation, your studies and your professional and scientific goals, as well as to answer knowledge questions at Life Science Bachelor’s level. The interview will be conducted with an online meeting tool.The test and the interview are scored and ranked.Criteria The criteria for acceptance are based solely on performance. The geographical origin of the applicant has no influence on the decision. The admission requirements must be met in all cases. Applicants are evaluated according to the following system: Written test 60%Interview 40%The committee, consisting of the head of the degree program and representatives of the teaching staff, awards places to the applicants who score highest in the admission procedure. The admission procedure as a whole, including tests and assessment results, are documented in a transparent and verifiable manner.Waiting list If you are not offered a place in the degree program but your score is considered good in comparison to others, you will be placed on the waiting list. This means that if another person declines their offer of a study place for the upcoming winter semester, applicants from the waiting list will be contacted. This can happen at short notice and no deadline can be determined in advance. You will be informed immediately if you are offered a spot in the degree program. Rejection by the degree program If you receive a rejection after the admission process, you can reapply for the next winter semester as soon as the application window is open again. You will then have to reapply online, submit all the necessary documents and go through the entire admission procedure again.Acceptance of the study place You will be informed via e-mail about the opportunity of receiving a place in the degree program. Attached to that you will find your training contract and a number of regulations. You need to return the signed contract in time (clearly stated in the e-mail) to secure and accept your place in the degree program. The accounting department will forward you the invoice for the tuition fee separately. This may take a few days. The timetable for the respective degree program is expected to be online one to two weeks BEFORE the beginning of each semester. All other study-relevant information will either be sent to you via e-mail, or you will receive it at the beginning of the academic year.Cancellation from the applicant’s side If you are unable or unwilling to accept your place in the degree program, please inform the Secretary's Office at biotechnologie@fh-campuswien.ac.at as soon as possible. Your place will then be allocated to the next person on the waiting list. Cancellations or withdrawal from the training contract will only be accepted in writing.
Dates Application period: 1st January to 27th March 2022Written admission test: expectedly 25th-28th April 2022Online interview: expectedly 16th – 25th May 2022
> FH-Prof. Mag. Dr. Beatrix Kuen-Krismer Head Department Applied Life Sciences, Head of Degree Program Molecular Biotechnology T: +43 1 606 68 77-3501bea.kuen@fh-campuswien.ac.at
> FH-Prof. Univ.Doz. Dr. Ines Swoboda Head of Competence Center Molecular Biotechnolog, Academic Staff