FH-Prof. Univ.Doz. Dr. Ines Swoboda Head of Competence Center Molecular Biotechnolog Academic Staff email@example.com T: +43 1 606 68 77-3507 F: +43 1 606 68 77-3509 Room: OG.F.05 Helmut Qualtinger Gasse 2 1030 WienLectures 2021/22Applied Life Sciences> Virology VO Molecular Biotechnology moreVirology VOLector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda0.5SWS1ECTSLecture contentsBasics in Virology: (a) Bacteriophages: morphology, replication, growth and quantification, application in biotechnology - examples (b) animal viruses: morphology, replication, pathogenesis, examples (retro viruses, influenza virus)Assessment methodsWritten examTeaching methodsLectureLanguageGerman-English> Biochemistry I: Foundations & Building Blocks … Molecular Biotechnology moreBiochemistry I: Foundations & Building Blocks of Life VOLector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1.5SWS2ECTSLecture contentsThe students are taught the physical, chemical and cellular basics of the design and molecular structure of biomacromolecules (proteins, nucleic acids, polysaccharides and lipids). A special focus is on the importance of carbon for the chemistry of living organisms and on the important role of water for the structure and function of biomacromolecules. In Addition, amino acids and proteins, sugars and polysaccharides, as well as fatty acids and lipids are explained in detail. The chemistry of the covalently linked monomers (amino acids, monosaccharides, fatty acids) is always considered first and then the structure of the macromolecules and supramolecular complexes is described. The following points are particularly pointed out: 1) that the unique structure of the macromolecules determines their function, 2) that non-covalent interactions play a decisive role in the structure and function of the macromolecules and 3) that monomers of the polymeric macromolecules have a specific sequence, which provides the information for the order of life.Assessment methodsWritten exam; open questionsTeaching methodsLecturesLanguageGerman> Molecular Biological & Biophysical Methods SE Molecular Biotechnology moreMolecular Biological & Biophysical Methods SELector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda, FH-Prof. Dr. Herbert Wank1.5SWS3ECTSLecture contentsTopics: Detection of Nucleic Acids PCR Western blot Growth of Microorganisms Antibodies and their use in Molecular Biology Centrifugation Protein Purification Southern and Northern blot Primer and Hybridization Proteinexpression Microarray Flurescence in Molecular Biology Sequencing Isolation and Purification of Nucleic Acids from various Organisms Primer and Hybridisation Primer design for cloning of a geneAssessment methodsPreparation, Oral Presentation, Participation in Discussions, written exam at the end of the seminarTeaching methodsSeminar, topic preparation in small groups (4-5), oral presentation in small groups (9-10), 15 minutes presentation, discussion, preparation of a handoutLanguageGerman> Infection Biology VO Molecular Biotechnology moreInfection Biology VOLector: Priv. Doz. Dr. rer. nat. habil. Holger Scholz, Professor und Direktor, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda2SWS2ECTSLecture contentsIn this lecture, beside the basics of medical microbiology, the complex interactions between pathogens and the human host are presented and the molecular, cellular and immunological aspects of this interaction are explained. Strategies developed by bacteria, viruses, fungi and parasites to colonize, invade, survive, reproduce and spread are discussed. Furthermore, the cellular and systemic effects on the host, the host's defence mechanisms and the clinical manifestations of the infectious diseases are shown. In addition, principles of the diagnosis of infectious diseases as well as antimicrobial and antiviral treatment options are explained and concepts behind the development of novel diagnostic tools, drugs and vaccines for future prevention and therapy of infectious diseases are presented. The lecture is rounded off by a detailed presentation of selected infectious diseases using clear visual material and a presentation of own research activities.Assessment methodsFinal exam Written exam in the end of the lecture courseTeaching methodsLectureLanguageEnglish> Allergies & Autoimmune Diseases VO Molecular Biotechnology moreAllergies & Autoimmune Diseases VOLector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS2ECTSLecture contentsIn this lecture course the molecular and cellular mechanisms of allergies and other hypersensitivity reactions are explained and the symptoms, causes and risk factors of allergic diseases are described. Furthermore, advantages and disadvantages of current diagnostic tests and therapeutic possibilities are discussed and strategies for improvement of diagnosis and therapies of allergies are introduced. This lecture course also explains the pathomechanisms underlying autoimmune disorders and describes determinants (such as genetic predisposition or environmental factors) that influence the development autoimmunity. In addition, the pathogenesis, clinical manifestation and the treatment possibilities of a few selected autoimmune diseases (e.g., Rheumatoid Arthritis, Multiple Sclerosis) are discussed. Furthermore, this lecture course also highlights similarities and differences between allergies and autoimmune disorders.Assessment methodsFinal exam Written exam after the last lectureTeaching methodsLectureLanguageEnglish> Molecular Immunology Lab UE Molecular Biotechnology moreMolecular Immunology Lab UELector: Kay Holleis, BSc MSc, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda3SWS3ECTSLecture contentsIn the Molecular Immunology laboratory the theoretical immunological knowledge is deepened and practically applied to research problems from the field of allergy research. Students work in small groups of 2 to 3 people on a scientific research question. As a team they have to find the best way to answer the research question, they have to design and perform the experiments using state-of-the-art immunological and molecular biological methods such as ELISAs, SDS-PAGE, immunoblotting, PCR, microscopy and flow cytometry. Finally, each student writes a laboratory report in the format of a scientific publication, in which the background of the research topic is summarized and the experimental work, the results and the conclusion are described.Assessment methodsContinuous assessment Continuous assessment, active participation, reportTeaching methodsLaboratoryLanguageEnglish> Molecular Immunology SE Molecular Biotechnology moreMolecular Immunology SELector: FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course research papers from internationally respected high-quality journals from the field of Molecular Immunology are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.Assessment methodsContinuous assessment Participation in discussion (Seminar paper)Teaching methodsSeminarLanguageEnglish> Scientific Method: Immunology SE Molecular Biotechnology moreScientific Method: Immunology SELector: FH- Prof.in Mag.a Dr.in Marianne Raith, FH-Prof.in Univ.Doz.in Dr.in Ines Swoboda1SWS1ECTSLecture contentsIn this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Immunology), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency. Finally each group presents its research project.Assessment methodsFinal exam Presentation and discussion of the developed strategyTeaching methodsSeminarLanguageEnglishPublications The publications of Ines Swoboda written at FH Campus Wien can be found in our publication database, others in the personal web space.