Details

Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

Academic Staff


T: +43 1 606 68 77-3601
F: +43 1 606 68 77-3609

Room: Büro01
Muthgasse 62
1190 Wien


Lectures 2019/20

Applied Life Sciences

> Bachelor Thesis - Supervision - BVT VO+UE
Bioengineeringmore

Bachelor Thesis - Supervision - BVT VO+UE

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Ing. DI (FH) Dr. Harald Kühnel, MSc, FH-Prof. DI Dr. Michael Maurer

2 SWS
2 ECTS
> Bioreactors and Bioprocess Engineering ILV
Bioprocess Technologymore

Bioreactors and Bioprocess Engineering ILV

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, FH-Prof. DI Dr. Michael Maurer

2 SWS
4 ECTS

Lecture contents

After the introduction, where the basic concepts and principles of bioprocess engineering are explained, the main bioreactor types and operation modes are presented. In the following section the kinetics of bioprocesses together with the underlying equations and graphs are outlined. Heat and mass transfer correlations, which are essential to be familiar with - especially for the design of bioreactors, are dealt in the following section. The characterization of various bioreactor types including enzyme reactors as weell as the upscaling principles are main topics of this lecture. Finally the basics of the sterilization technology and the design of SIP procedures are elucidated.
The understanding as well as the benefit of the presented model equations for the particular unit operations are shown by some selected examples.

Assessment methods

Two written intermediate exams and a final test.

Teaching methods

The teaching is based on the following concept:
First the scientific principles involved in a specific unit operation within biochemical engineering together with their practical application are elucidated. After a thorough discussion on the limitations of the respective Mathematical Model its practical value is shown by some examples.

> Biosafety and Biosecurity VO
Bioprocess Technologymore

Biosafety and Biosecurity VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Mag. Dr. Andreas Franz

1 SWS
2 ECTS

Lecture contents

This course willl convey concepts and requirements for biological safety, as well as occupational health and safety, as covered in EN 45000.
In this context the course will include a discussion of biological risk, followed by related and required measures measures as defined by the risk classes and the austrian VbA.

Assessment methods

Final Exam

Teaching methods

Lectured Course

Language

German-English

> Biosafety and Biosecurity VO
Biotechnological Quality Managementmore

Biosafety and Biosecurity VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Mag. Dr. Andreas Franz

0.5 SWS
1 ECTS

Lecture contents

This course willl convey concepts of biological safety, as defined by occupational and health requirements, and biological security.
In this context it will include a discussion on assessment critieria for biological safety and present the biological risk Groups. This will be followed by a discusion of the technical measures as defined by the risk classes. This will complete with a brief view into further aspects of biosafety and a personal work report as medical laboratory analyst in the recent Ebola epidemic in africa.

Assessment methods

Final Exam

Teaching methods

Lectured Course

Language

German-English

> Facility Design, GMP-Project, Bachelor Thesis SE
Bioengineeringmore

Facility Design, GMP-Project, Bachelor Thesis SE

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Ing. DI (FH) Dr. Harald Kühnel, MSc, FH-Prof. DI Dr. Michael Maurer

5 SWS
10 ECTS
> General Microbiology VO
Bioengineeringmore

General Microbiology VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

2 SWS
4 ECTS

Lecture contents

Abreviated contents:
The Cell: General properties, systematics, Growth
Prokaryotes, Fungi and Algae
Microbial Habitats

For contents see above.

Assessment methods

Written Exam

Teaching methods

Combination of lectured course and film presentations

Language

German

> GMP (practical Course) SE
Bioengineeringmore

GMP (practical Course) SE

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
4 ECTS

Lecture contents

The course will be held in German - see German description

Assessment methods

Continuous assessment, course work

Teaching methods

The course will be held in German - see German description

> Introduction to GMP and Quality Management VO
Bioengineeringmore

Introduction to GMP and Quality Management VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
2 ECTS

Lecture contents

Terms, principles, concepts and practice of today´s Quality Management and in particular of good manufacturing practice;
processes and operating procedures, manufacturing documents;
models and Standards;
the concept of error and its general relevance;
GMP: legal Framework and purpose;
selected subjects and aspects of GMP.

Assessment methods

Written exam + practical exercise

Teaching methods

Lecture with discussion
Homework

Language

German

> Introduction to GMP and Quality Management VO
Biotechnological Quality Managementmore

Introduction to GMP and Quality Management VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
2 ECTS

Lecture contents

Terms, principles, concepts and practice of today´s Quality Management and in particular of good manufacturing practice;
processes and operating procedures, manufacturing documents;
models and Standards;
the concept of error and its general relevance;
GMP: legal Framework and purpose;
selected subjects and aspects of GMP.

Assessment methods

Written exam + practical exercise

Teaching methods

Lecture with discussion
Homework

Language

German

> Selected topics in Quality Management VO
Biotechnological Quality Managementmore

Selected topics in Quality Management VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Dipl.-Ing. Gerald Holzmann, Bakk. techn.

1 SWS
2 ECTS
> Specific Microbiology VO
Bioengineeringmore

Specific Microbiology VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

2 SWS
4 ECTS

Lecture contents

This course will present the following aspects of applied microbiology based on selected examples:
microoorganisms in association with Foods
microorganisms in the environment
pharmaceutical indicator organisms
production strains for biopharmaceuticals

Assessment methods

Written final exam

Teaching methods

Lectured course and distant learning

Language

German-English

> Sterilization and Disinfection ILV
Bioprocess Technologymore

Sterilization and Disinfection ILV

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
2 ECTS

Lecture contents

Terms and overview of processes for microbial inactivation
Processes of moist heat inactivation, as well as chemical and thermal disinfection
Predictive calculation models

Assessment methods

written exam

Teaching methods

Lectured course

Language

German-English

> Sterilization and Disinfection ILV
Biotechnological Quality Managementmore

Sterilization and Disinfection ILV

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
2 ECTS

Lecture contents

Terms and overview of processes for microbial inactivation
Processes of moist heat inactivation, as well as chemical and thermal disinfection
Predictive calculation models

Assessment methods

written exam

Teaching methods

lectured course

Language

German-English

> Technical Microbiology VO
Bioengineeringmore

Technical Microbiology VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Dipl.-Ing. Stefan Panuschka

2 SWS
3 ECTS

Lecture contents

Industrial application of microorganisms and Industrial Bio-Products
Primary and secondary metabolites
Antibiotics
Enzymes and other products

Betalaktams
Biosynthesis of Penicillin and Cephalosporin and strains
Early development
Mould-based Production Technology, productivity and economic constraints
Selected process control parameters
Aspects of Scale-Up
Downstream Processing
Isolation, purification, pharmaceutical tabletting
Regulatory framework and Summary

Assessment methods

Final written examination

Teaching methods

lectured course

Language

German-English