Details

Lecture contents

After the introduction, where the basic concepts and principles of bioprocess engineering are explained, the main bioreactor types and operation modes are presented. In the following section the kinetics of bioprocesses together with the underlying equations and graphs are outlined. Heat and mass transfer correlations, which are essential to be familiar with - especially for the design of bioreactors, are dealt in the following section. The characterization of various bioreactor types including enzyme reactors as weell as the upscaling principles are main topics of this lecture. Finally the basics of the sterilization technology and the design of SIP procedures are elucidated.
The understanding as well as the benefit of the presented model equations for the particular unit operations are shown by some selected examples.

Assessment methods

Two written intermediate exams and a final test.

Teaching methods

The teaching is based on the following concept:
First the scientific principles involved in a specific unit operation within biochemical engineering together with their practical application are elucidated. After a thorough discussion on the limitations of the respective Mathematical Model its practical value is shown by some examples.

Lecture contents

This course willl convey concepts and requirements for biological safety, as well as occupational health and safety, as covered in EN 45000.
In this context the course will include a discussion of biological risk, followed by related and required measures measures as defined by the risk classes and the austrian VbA.

Assessment methods

Final Exam

Teaching methods

Lectured Course

Language

German-English

Lecture contents

This course willl convey concepts of biological safety, as defined by occupational and health requirements, and biological security.
In this context it will include a discussion on assessment critieria for biological safety and present the biological risk Groups. This will be followed by a discusion of the technical measures as defined by the risk classes. This will complete with a brief view into further aspects of biosafety and a personal work report as medical laboratory analyst in the recent Ebola epidemic in africa.

Assessment methods

Final Exam

Teaching methods

Lectured Course

Language

German-English

Lecture contents

Abreviated contents:
The Cell: General properties, systematics, Growth
Prokaryotes, Fungi and Algae
Microbial Habitats

For contents see above.

Assessment methods

Written Exam

Teaching methods

Combination of lectured course and film presentations

Language

German

Lecture contents

The course will be held in German - see German description

Assessment methods

Continuous assessment, course work

Teaching methods

The course will be held in German - see German description

Lecture contents

Terms, principles, concepts and practice of today´s Quality Management and in particular of good manufacturing practice;
processes and operating procedures, manufacturing documents;
models and Standards;
the concept of error and its general relevance;
GMP: legal Framework and purpose;
selected subjects and aspects of GMP.

Assessment methods

Written exam + practical exercise

Teaching methods

Lecture with discussion
Homework

Language

German

Lecture contents

Terms, principles, concepts and practice of today´s Quality Management and in particular of good manufacturing practice;
processes and operating procedures, manufacturing documents;
models and Standards;
the concept of error and its general relevance;
GMP: legal Framework and purpose;
selected subjects and aspects of GMP.

Assessment methods

Written exam + practical exercise

Teaching methods

Lecture with discussion
Homework

Language

German

Lecture contents

This course will present the following aspects of applied microbiology based on selected examples:
microoorganisms in association with Foods
microorganisms in the environment
pharmaceutical indicator organisms
production strains for biopharmaceuticals

Assessment methods

Written final exam

Teaching methods

Lectured course and distant learning

Language

German-English

Lecture contents

Terms and overview of processes for microbial inactivation
Processes of moist heat inactivation, as well as chemical and thermal disinfection
Predictive calculation models

Assessment methods

written exam

Teaching methods

Lectured course

Language

German-English

Lecture contents

Terms and overview of processes for microbial inactivation
Processes of moist heat inactivation, as well as chemical and thermal disinfection
Predictive calculation models

Assessment methods

written exam

Teaching methods

lectured course

Language

German-English

Lecture contents

Industrial application of microorganisms and Industrial Bio-Products
Primary and secondary metabolites
Antibiotics
Enzymes and other products

Betalaktams
Biosynthesis of Penicillin and Cephalosporin and strains
Early development
Mould-based Production Technology, productivity and economic constraints
Selected process control parameters
Aspects of Scale-Up
Downstream Processing
Isolation, purification, pharmaceutical tabletting
Regulatory framework and Summary

Assessment methods

Final written examination

Teaching methods

lectured course

Language

German-English