Details

Dr. Elisabeth Riegel

Academic Staff


T: +43 1 606 68 77-3543
F: +43 1 606 68 77-3509

Room: OG.F.02
Helmut Qualtinger Gasse 2
1030 Wien


Lectures 2021/22

Applied Life Sciences

> Signalling Pathways Lab UE
Molecular Biotechnology more

Signalling Pathways Lab UE

Lector: Andrea Krames, BSc MSc, Dr.in Elisabeth Riegel

3SWS
3ECTS

Lecture contents

Methods for the manipulation and the analysis of signalling pathways in cell culture are applied, broadening the knowledge on specific pathways. The applied methods are transient transfection in cell culture, reporter constructs with gfp and luciferase, overexpression of activators/repressors (including RNAi), Western analysis of cellular extracts, analysis of phosphorylation, fluorescence microscopy of labelled proteins and pharmacologic manipulation of the pathways.

Assessment methods

Final exam
Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experiments. (Seminar paper)

Teaching methods

Laboratory work

Language

English

> Toxicology Lab UE
Molecular Biotechnology more

Toxicology Lab UE

Lector: Kay Holleis, BSc MSc, Dr.in Elisabeth Riegel

3SWS
3ECTS

Lecture contents

The toxicological and therapeutic potential of a small molecule drug will be estimated with a variety of cell based test systems. On the one hand the activating potential of the small molecule on a specific pathway (heat shock response pathway) is analysed and on the other hand possible cytotoxic effects are estimated in a concentration-dependent manner. A broad variety of assays is provided for the students including luciferase reporter assays, Western blot, qPCR, flow cytometry, ELISA and general viability assays. The students themselves select suitable methods.

Assessment methods

Continuous assessment
Assessment of the work in the laboratory, written exams at the beginning of the laboratory course, discussion of the results after the laboratory course and a written report of the experiments

Teaching methods

Practical course with independent performance of the experiments.

Language

English

> Drug Discovery SE
Molecular Biotechnology more

Drug Discovery SE

Lector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel

1SWS
1ECTS

Lecture contents

In this course research papers from internationally respected high-quality journals from the field of Drug Discovery are distributed to the students who read them on their own. The seminar itself then takes the format of a peer-group discussion, where students present the background, the most important findings and the conclusion of the publications. Furthermore, they discuss the strengths and the weaknesses of the publications and make suggestions for improvements.

Assessment methods

Final exam
Participation in discussion (Seminar paper)

Teaching methods

Seminar

Language

English

> Scientific Method: Drug Discovery SE
Molecular Biotechnology more

Scientific Method: Drug Discovery SE

Lector: FH-Prof. Dr. Thomas Czerny, Dr.in Elisabeth Riegel

1SWS
1ECTS

Lecture contents

In this course the students learn strategies of scientific research. In a small group they develop a strategy for a given topic (in Drug Discovery), by designing experiments and work packages which they evaluate according to different criteria like costs, effort, efficiency, Finally each group presents its research project.

Assessment methods

Final exam
Presentation and discussion of the developed strategy

Teaching methods

Seminar

Language

English

Publications

The publications of Elisabeth Riegel written at FH Campus Wien can be found in our publication database, others in the personal web space.