The path from gene to product: biotechnology or bioengineering is the engineering discipline of biotechnology. It concerns optimizing and developing biotechnological methods for efficient production in the industry. The degree program is tailored specifically to the needs of industrial applications: pharmaceutical production, the chemical industry and brewing and fermentation technology. A bio-industrial pilot plant at the university provides unique opportunities for a practical and application oriented education.
Elisabeth BeckElisabeth Holzmann, Bakk.techn.Johanna BauerMag.a Susanne PolanskyMuthgasse 621190 Vienna T: +43 1 606 68 77-3600 F: +43 1 606 68 firstname.lastname@example.org
Office hours during semesterMon. to Thu. 4:30 p.m. to 6:00 p.m.
By appointmentMon. to Thu. 10:00 a.m. to 6:00 p.m.Fri. 10:00 a.m. to 1:00 p.m.
Application period for academic year 2018/19
1st November 2017 to 15th June 2018
tuition fee / semester:
+ ÖH premium + contribution**
* Tuition fees for students from third countries € 727 per semester
**for additional study expenses (currently up to €83 depending on degree program and year)
You are interested in the practical application of biology and technology in the industry. Mathematics is one of your strengths. You also have good knowledge of natural sciences. You enjoy working in a team and on projects. You are a process-oriented and analytical thinker and are highly conscious of quality. You find a career in the industry attractive. Average English skills are expected. Language of instruction is German
Your education and research benefit from our close partnerships with well-known biotech companies as well as the University of Natural Resources and Life Sciences, Vienna (BOKU) and the Vienna Institute of Biotechnology (VIBT), who share the campus with us. The partnership enables you to take advantage of the BOKU's excellent infrastructure. In addition to the laboratories, this includes an industrial pilot plant with which production processes can be developed on a laboratory scale and applied on a pilot scale. This provides you with a practice-oriented education, because in the industry the lab and pilot scale is only followed by the production scale in which the product is manufactured in commercially viable quantities. The simulation of the processes on a pilot scale helps determine deviations in each process step and develop process parameters for the commercial evaluation of the production processes. Numerous R&D projects in the degree program offer you the opportunity to work with cutting-edge applications and to make valuable contacts for your future career. Practical relevance is also guaranteed at our Campus Lecture evenings, which are open to all and feature contributions from prominent experts.
The practically oriented degree program has established itself in applied research and development. It concerns optimizing bioengineering methods for industrial production. The degree program focuses on three industrial applications: red and white biotechnology as well as brewing and fermentation technology. The red biotechnology includes medical and pharmaceutical applications. The white biotechnology plays an increasingly important role in the chemical industry and other industries.
The benefits of biotechnology are that fewer natural resources are used, energy efficiency is higher, CO ² emissions are lower and production costs are also lower. The fact that the degree program is particularly application oriented can also be seen within the context of R&D projects. For example, the Department of Bioengineering together with the biotech company Vogelbusch developed a process improvement that helps to replace petroleum as the basis for chemicals with less expensive renewable raw materials.
With Bioengineering you have chosen an intensive technical and scientific education. Technology, biology and chemistry are the foundation of the degree program.
Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem
Abreviated contents:The Cell: General properties, systematics, GrowthProkaryotes, Fungi and AlgaeMicrobial HabitatsFor contents see above.
Combination of lectured course and film presentations
Lector: Ao. Prof. Dr. Matthias Weil, Priv.Doz.DI Dr.techn. Peter Weinberger
Elements and compounds; atoms and the periodic table of the elements; the chemical bond; molecular geometries; gases, liquids and solid state; preservation of mass and energy; chemical equilibrium; oxidation and reduction; coordination compounds; basics of chemical thermodynamic; main group and transition metal chemistry; environmental problems; important aspects of general and inorganic chemistry in biological systems.
At the end of the lecture there will be a written examination
Lecture with exercises
Lector: Ing. DI (FH) Dr. Harald Kühnel, MSc, Regina Schlager, MSc, Dr.in Michaela Zeiner
Introduction into Analytical Chemistry - Basics and Methods; validationSpectroscopic methods: AAS, AES, RFA, REM; UV/VIS, IR, MS, XPS, NMR.Classical quantitative analysis: gravimetry, titrimetry (Acid-base titrations, precipitation titrations, titrations based on complexation reactions, titrations based on redox reactions).Electrochemical methods of analysis: electrogravimetry, coulometry, conductometry, potentiometry, polarography.Introduction to chromatography
oral presentation followed by short written essay in small groupswritten exam at end of semester
interactive class lecture
Lector: Alexandra Hofinger, Matthias Kubek, BSc, Thomas Schmidt, DI Petra Viehauser, Martin Viehauser, Dr.in Michaela Zeiner
The focus is gaining experience in important basic principles and physical-chemical procedures of analytic and quantitative chemistry as well as chemical basic operations.Introductory part ( 7 exercises)
An examination will be held after the finalisation of the introductory part.The results of the written examination and the practices will be taken as basis for assessment.
Practices; on-the-job training
Lector: DI Dr. Daniel Dangl
- chemical bonds in organic chemistry- basic concepts of organic chemistry- introduction to organic compounds- overview on functional groups- basics of organic reactions
Lector: a.o.Univ. Prof. Dr. Mag. Manfred Kühleitner
equations functions in one variabledifferential and integral calculusordinary differential equations
1. Active participation2. Weekly homeworks 3. A final examination
Lecture + Excersise
Lector: Dr. Jutta Mattanovich, DI Beatrix Mayer-Reinprecht, Ao Univ. Prof. Dipl.-Ing. Dr. Paul Messner, Dipl.Ing. Dr. Christine Prenner, Johanna Schilcher
- Introduction into light microscopy / Structure and function of simple cellular systems.- Cellular organization of microorganisms (yeast, bacteria) and plants / cell wall, typical organelles of higher organisms (e.g. nucleus, vacuole(s), ER, etc.) / Function of plasmatic and non-plasmatic components (e.g. osmosis, permeability, nutrient uptake, storage, etc).
- After the course written examination about theoretical aspects and assessment of the graphical documentation (workbook) of the microscopy work / active participation
- Powerpoint presentations / practical experiments in the microbiology laboratory
Lector: Dr. Christian Rupp
1. Units and quantities2. Mechanics3. Thermodynamics4. Electricity5. Optics
Lector: Univ.-Prof. Dipl.-Ing. Dr. Werner Timischl
1-dimensional data description:Population and sample, numerical measures for location and spread, boxplot, absolute and relative frequency, empirical distributions.Random variables:Probability (axioms, addition rule, conditional probability, multiplication rule); discrete random variables (binomial distribution, hypergeometric distribution); continuous random variables (normal distribution).Parameter estimation:Estimation functions, confidence intervals (mean, standard deviation, probabilty).Testing of hypotheses:Introduction (alternative and null hypothesis, 1- and 2-sided hypotheses, types of errors, power);1-sample problems (t-, binomial-test); test of normality (QQ-plot, Shapiro-Wilk-test); 2-sample problems (t-, F-test); sample size calculations (t-test).Linear regression:Bivariate normal distribution, Pearson correlation coefficient; simple linear regression (least squares estimation, test on linear relationship, coefficient of determination, regression through the origin, linearization methods); linear calibration functions.
Lecture with case studies and exercises; accompanying text to lecture, collection of formulae and simulations programs (in R) for downloading.
Lector: DI Petra Viehauser
Following topics will be presented:Atomic weight/molecular weight/mole /laws of stoichiometry/balancing chemical reactions/redox reactions, solutions/units of concentration/Chemical equilibrium/Ideal GasesAcids and bases and their salts, buffers, the pH-scale, and pH-calculation/Solubilityvolumetric analysis/ Calibration Procedure and validation of Analytical Methods/ dilution/ buffer/ calculation of culture medium / exercises in photometric determination with calibration graph
Four written midterm exams.Some examples have to be calculated. If not, there is the possibility to repeat this examples.Homework.
Power Point is used to present the theory of the subjects, we calculate many exercises during the lecture, active collaboration is requested. The script, the homework and additional exercises will be available in time on the moodle platform.
Lector: Dipl.-Ing. Dr.mont. Paul Surer
Repetition and strengthening of fundamental mathematical concepts and methods.In particular, we will focus on the following items.1) terms, factions, complex fractions, equations2) powers, exponential function, logarithm3) trigonometric functions4) basic linear algebra (vectors)
written tests, written assignments, performance
Lector: Ao Univ. Prof. Dipl.-Ing. Dr. Paul Messner
Bioorganic chemistry combines methods and techniques of organic chemistry and biochemistry to solve problems of biological relevance and it is inspired by biology when new biotechnological processes are developed.- Introduction into Bioorganic Chemistry- Description of the essential structural elements: nucleotides, amino acids, carbohydrates, lipids (partly repetition)- Assembly and structure of peptides, proteins and biomembranes - overview- Methods for characterization of these componentsIn the course of the lecture different prokaryotic and eukaryotic systems will be compared:- The model bacterial glycoproteins will be used to demonstrate obvious differences to eukaryotic glycosylation systems and possible biotechnological applications will be discussed- Description of the orientation system of magnetotactic bacteria- Biological Self-assembly- Biomineralization- Molecular Biomimetics
One interim test and a final written exam. Single/multiple choice questions and open questions are mixed
Predominantly lecture style instructions.The slides will be made available to the students within the FH Portal; they are derived from both the suggested text books and the indicated literature references (on the slides).
Lector: Matthias Kubek, BSc, Thomas Schmidt, DI Petra Viehauser, Martin Viehauser, Dr.in Michaela Zeiner
During this course you will try some quantitative methods. The focus is gaining experience in important basic principles and physical-chemical procedures of analytic and quantitative chemistry as well as chemical basic operations.Introductory part (+6 samples)1. Sample: Knowledge Base - titration and uncertainty of measurement2. Sample: Weak Acid, acidimetric3. Sample: Gravimetric determination of iron4. Sample: Water analysis - determination of water hardness5. Sample: Distillation and determination of nitrogen content (Parnas-Wagner)
An examination will be held. The results of the written examination and the practices will be taken as basis for assessment.
1. Sample: Conductometric determination of saltsolution2. Sample: Potentiometric determination of the molecular weight of an amino acid3. Sample: Determination of chloride beside jodide with an ion-selective electrode4. Sample: Photometric determination of iron5. Sample: Photometric determination of the pK-value of an indicator6. Sample: Redoxtitration (Vitamin C, jodemetric)7. Sample: Ion chromatography (chloride, nitrate and sulfat)
Litte oral test before starting working.An examination will be held at the end of the course.The results of the written examination and the practices will be taken as basis for assessment.
Lector: Dipl.-Ing. Andreas Klingler
-introduction to Fluid Dynamics-physical properties of fluids-fundamentals of hydrostatics-hydrdynamics: conservation equations-pipe hydraulics-sedimentation velocity-pumps and pump design- stirring-dimension analysis and Scale UpThe theoretical content of the course is used for practical application at the end of each chapter.
Written exam at the end of the course.
theoretical lecture with powerpoint and blackboard, practical examples
Lector: Univ.-Prof. DI Dr. Herbert Braun
The first part of the lecture will give an overview of the most important engineering materials as metallic- and no metallic materials as ceramic materials, glass, plastics and composite materials. This part is supplemented by the explanation of corrosion and corrosion protection.in the second part production processes are discussed - casting and sinter, forging, rolling, milling, drilling, sawing and grinding, welding, soldering and bonding.in the last part of lecture machine elements are discussed.
Lector: Dr. Matthias Müllner
Overview on methods in microbiology as a detailed preparation for the practical courses ('Laborpraktikum')1. Aseptic techniques2. Cultivation of MO3. Identification of MO4. Determination of growth kinetics5. Antibiotics
Final written examination
Lecture with practical application examples
1. Structural untis of organic compounds (hybride orbitales, molecular orbitales)2. Reaction mechanisms3. Alkanes (characteristics, introduction to nomenclature, reactions, synthesis, sources, representatives)4. Alkenes (isomerism, reactions, representatives)5. Alkynes (representatives, characteristics, sources, reactions)6. Halides (characteristics, synthesis, representatives, reactions)7. Alcoholes (characteristics, synthesis, reactions, representatives of mono- and polyols)8. Ethers (characteristics, synthesis, reactions)9. Sulfor containing compounds10. Amines (characteristics, synthesis, reactions, representatives), further N- and P-compounds11. Aldehydes and ketones (characteristics, synthesis, reactions, representatives)12. Carbonic acids (characteristics, synthesis, reactions, representatives)13. Derivatives of carbonic acids (halides, esters, amides, anhydrides)14. Amino acids and peptides15. Aromatic Compounds (aromaticity, characteristics, reactions, representatives)16. Dicarbonic acids17. Hydroxy carbonic acids18. Organometallic Compounds19. Natural Compounds (carbohydrates, fats, oils, waxes, terpens, nucleic acids)
recurring tests, exercise examples and final examination
Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Univ.-Prof. Dipl.-Ing. Dr. Werner Timischl
This course will present the following aspects of applied microbiology based on selected examples:microoorganisms in association with Foodsmicroorganisms in the environmentpharmaceutical indicator organismsproduction strains for biopharmaceuticals
Written final exam
Lectured course and distant learning
Lector: Dipl.-Ing. Andreas Klingler, Dipl.-Ing. Dr.mont. Paul Surer
The main focus of this course will be numerical and applied mathematics. The first part will deal with aspects of numerical mathematics with an emphasis on the solution of systems of linear equations. This is followed by interpolation techniques eventually leading to numerical differentiation. Finally, this first part is concluded by an introduction to numerical integration. The second part of the course will deal with applied mathematics where the theory from Hydrodynamics is used to analyze real world examples.
written exam + practical exercises
Powerpoint presentation assisted by calculation of practical examples
Lector: Markus Pichler, MSc
As a basic course of Mechanical Engineering, the following content has to be conveyed:1) instrcution to technical drawing 2) descriptive geometry (2D, 3D, sectional views, dimensioning)3) details for manufacturing (tolerances, fits, connections, surface processing, welding symbols)4) process flowcharts (basic flow chart, process flow diagram, P&ID)
There will be no written exam within this course. The assessment will be based on the level of cooperation and a written home exercise.
lecture with case studies and partly short exercises.
Lector: Dr. Matthias Müllner, Johanna Schilcher, Fabian Schneider, Mag. Helga Weisse
Introduction into microbiological techniques:Working under sterile conditionsDifferent cultivation techniques (surface cultures, liquid cultures)Cell number determination (according to Koch, Thoma chamber)Preparation of microbial mediaMorphology:Microscopic imaging of bacteria, yeast and filamentous fungiStaining techniques. Gram, capsule and spore stainingPhysiology:Growth of yeast on different carbon sources (C-auxanogram)Antibiotics testing (diffusion test, commercial test stripes, dilution method)Api test (physiological identification of bacteria with different biochemical tests)Growth kinetics:Growth characteristics of E. coli
Bonus system for practical courses. Final written examination (joint exam with MiMe)
Practical course; in the first part, the students perform experiments under guidance of the lecturers; in the second part, the acquired skills have to be applied in order to autonomously identify an exemplary germ
Lector: Ao.Univ.-Prof. Dipl.-Ing. Dr. Erwin Ivessa
Basic substances in Biochemistry (Short repetition from SS): Carbohydrates, amino acids, lipids, nucleotides; isomerisms, electrolytesPeptides and proteins: Composition, structure, functionOverview of protein methodsHemoglobinEnzymes: Basics, catalysis, mechanisms, kinetics, inhibition, regulationIntermediary metabolism: Basics, energetic considerationsImportant metabolic pathways:Carbohydrate metabolism: Glycolysis, fermentations, citrate cycle, calvin cycle, pentose phosphate pathway, glycogenLipid metabolism: Fatty acids, cholesterolBiological membranesRespiratory chain and oxidative phosphorylationOverview of amino acid and nucleotide metabolism; cata- and anaplerotic reactionsNitrogen metabolism, urea cyclePhotosynthesisDNA and RNA: Structure and functionReplication, transcriptionTranslation, posttranslational modificationsRegulation of gene expressionOptional: Molecular machines, intracellular sorting of proteins, signal transduction, immune system
Two interim tests and a final exam. Single/multiple choice questions and open questions mixed. Details to this matter will be discussed in the lectures.
Predominantly lecture style instruction. The slides used will be made available to the students within the FH Portal; they are mainly derived from the suggested text books
Lector: DI Dr. nat. techn. Matthias Hackl
Methods for Proteins:- Total protein concentration- Immunochemistry (ELISA)- Electrophoresis- Chromatography- Mass spectrometryEnzyme kinetics- Km-Value- Reaction ratesNucleic Acids
Homework, In-class contribution, Final Exam
Lecture with practical examples, which are done in the form of short projects during lectures or as part of homework
Lector: Dipl. Ing. Dr. Mohamed Hassan
Fundamentals of Electrical EngineeringApplications of ElectricityFundamentals of Electrical EngineeringBasic electrical variablesOhm's lawElectric power, work, efficiencyThe electrical circuit of consumersMeasuring electrical variableTypes of currentPower and safe handling of electricityPipework and electrical connectionElectrical Installation and ConnectionsProtective measures for electrical equipmentPossible errors on live equipmentDangers of ElectricitySafe handling of live wires and machinesSymbols on electrical machines DEVICES ANDElectric drive equipment in chemical plantselectric motorsThree-phase motorsDC motorsTypes of motor protection
Lecture with media support (power point slides). Accompanying Exercises and demonstration material e.g. sketching of circuits sketch and calculations, measuring instruments,..
Lector: DI Axel Foraschik
Applied Material Technology- Characteristics- Metallics- Plastics- Keramisch- Surface TechnologyMachines- Pumps- Agitators, Mixer- Homogenizers- Centrifuges- Machine SafetyEquipment- Pressure Vessels- Filter Housings- Heat ExchangerWater Treatment- Pretreatment- Filtration- Destillation
Written exam. Oral exam if written test negative.
Lecture with Powerpoint-presentation (presentation documents will be provided). Focus on presentation of examples out of industrial practice. Discussion and experience exchange of the students under presentation of the lector. Appliance of lecture contents in training examples.
Lector: Dipl.-Ing. Dr. Rafat Al Afif, Dipl.-Ing. Andreas Frohner, Dipl.-Ing. Denis Soldo
Fundamental operations of mechanical-thermal Process Engineering are discussed in ths lecture. Energy Management and technical Thermodynamics, applied Thermodynamics, mixing & stirring, oxigen transfer, mechanical separating processes, thermal separating processes, physico-chemical separating processes.
Knowledge on basics of molecular genetics:What are living organisms made of - in a biochemical sense - what molecules - which compartments and structures?How are these molecules, compartments and structures passed on to offspring?How do living organisms function in a chemical and physical sense?How is this live "steered"?How identical are offspring to their parents, or how different?How is genetic and biological relationship explained on the molecular level?Knowledge on basics recombinant DNA technology:Enzymatic modification of DNAAmplification of DNA - Polymerase Chain Reaction (PCR)Gene expression and cloningTransfer of DNA into host cellsIsolation of genomic and plasmid DNABacteriophages - biology and applicationQualitative and quantitative analytical methodsExpression systems/hosts/vectorsGenomics and Proteomics
Autonomous solving of problems related to the lecture Mechanical-Thermal Process Engineering
autonomous calculation of exercise examples, supported by tutors
Mathematical examples for process engineering operations
demonstration of mathematical examples with student participation, homework, distance learning
Lector: Ing. DI (FH) Dr. Harald Kühnel, MSc, Dr. Matthias Müllner, Regina Schlager, MSc
The lecture Bioanalysis (part 1) will cover the following topics:Immunological techniques like ELISA, SPR, Western-blot, Protein-arrays, IHC, …Techniques of cell biology like fluorescence microscopy, FACS, counting of cells, …Fundamental biochemical techniques like determining the concentration of protein solutions, …And instrumental analysis-techniques like electrophoresis, capillary-electrophoresis, FPLC, HPLC, Proteome-analysis, … .Part 2 of this lecture will be held as a seminar. Students are requested to select a recombinant protein independently and should prepare a presentation covering the following aspects:- Why was the respective host organism chosen?- Where does the GOI come from?- How was the recombinant host produced (cloning strategy)?- How was the recombinant protein expressed/produced and analyzedPresentations will be held as a mini-symposium and students may select between an oral presentation or a poster presentation. Discussions will further intensify the gained knowledge. In addition every student will have to prepare a one-page handout.
Part 1: Exam at the end of the lecturePart 2: No exam. In the grade integrated are the results of the presentation, of the active participation in the discussions of other speeches and the quality of the handouts.
Part 1: LecturePart 2: Presentation done by the students (speech or poster presentation) and discussion
Lector: Barbara Eckmair, Bakk. techn., Ing. DI (FH) Dr. Harald Kühnel, MSc, Stefanie Neuner, BSc, Thomas Schmidt, DI Dr. Gerhard Stadlmayr
Chemical Calculations, NiNTA Chromatopraphy, Dialysis, Enzyme activity assays, Enzyme kinetic assays, SEC and HPLC, Protein quantification (Bradford, OD280), SDS-PAGE, Western Blot, ELISA
In-class participation and written protocols
Practical training accompanied by discussion and reflection rounds
Lector: DI (FH) Thomas Sterovsky
Bioprocess Engineering Principles
Homework, Final Exam
Lector: Martin Huber, FH-Prof. DI Dr. Michael Maurer
Brewing Technology:Raw materials in brewing. Enzymatic processes during malting, mashing, boiling and fermentation&storage of beer. Filling technology in beverage industry.Analyses and assessment of quality control in breweries. beer design.beer tasting.
Lector: FH-Prof. DI Dr. Michael Maurer
Biological ExpressionsystemsCell BanksMedia DevelopmentSterilisationReactor EngineeringMass BalancesScale up, Process Design
final exame, written
Lector: Dipl.-Ing. Werner Seiler
Basic concepts of measurement, principles of electrical measurement of quantities with significance in biotechnological processes.Basics of sensor elements.Fundamentals of process automation, process control, in particular, programmable logic controllers (PLCs) and field bus systems.Introduction to the fundamentals of control theory, types of control systems, analysis, design and simulation of control loops.
Written test at the end of the lecture.
Lecture, design and calculation exercises with Excel and simulation programs.
Lector: FH-Prof.in Mag.a Dr.in Alexandra Graf, Anna Tomaselli, BSc
1. In this lecture we talk about what Bioinformatics is and why we need it today.2. Basic concepts of programming will be discussed and with hands on exercises illustrated.We will go through specific topics of Bioinformatics and discuss the available applications. The topics include:- Why did Bioinformatics develop and what is it.- Human Genome Project and its consequences- Biological sequences, sequence comparison and database search.- Pattern search- Structure of biological sequences and structure prediction- High throughput technologies and data analysis
Exercises and short test at end of the lecture
lecture, powerpoint presentation, discussion and hands on exercises
Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Dipl.-Ing. Stefan Panuschka
Industrial application of microorganisms and Industrial Bio-ProductsPrimary and secondary metabolitesAntibioticsEnzymes and other productsBetalaktamsBiosynthesis of Penicillin and Cephalosporin and strainsEarly developmentMould-based Production Technology, productivity and economic constraintsSelected process control parametersAspects of Scale-UpDownstream ProcessingIsolation, purification, pharmaceutical tablettingRegulatory framework and Summary
Lector: DI Dr. nat. techn. Matthias Hackl, FH- Prof.in Mag.a Dr.in Marianne Raith
The cell (Organization, cell compartments, Cytoskeleton); cell membrane (structure, properties, lipid and protein components, transport mechanisms); cell organelles.; cell nucleus, storage and information, gene therapy; proteins and their manifold functions; Bioenergetics; cell Division; Tissues; Cellular components of the immune system, genetic and epigenetic mechanisms to control cellular behavior
Powerpoint slidesDiscussion rounds following each chapter, to reflect on the presented information
Review of elementary concepts and methods;confidence intervals and tests (confidence intervals for binary variables, robust statistics, outliers, equivalence tests);acceptance sampling ( sampling plans for attributes and variables);control charts;simulation experiments (confidence intervals, bootstrapping, p-value, power);design of experiments (parallel design, one-way ANOVA, simple linear regression, calibration experiments, inter laboratory tests.
Lecture combined with exercises
Terms, principles, concepts and practice of today´s Quality Management and in particular of good manufacturing practice; processes and operating procedures, manufacturing documents; models and Standards; the concept of error and its general relevance;GMP: legal Framework and purpose;selected subjects and aspects of GMP.
Written exam + practical exercise
Lecture with discussionHomework
Lector: Dr. Christian Leitner, Dr. Matthias Müllner, Dr. Matthias Steiger
Goal:Establish a plan to produce lactic acid in yeast. Develop a concept including all relevant points and present it to your client. Goal of this seminar is to clone the L-lactat dehydrogenase gene (LDH, EC 22.214.171.124) into a yeast strain. This will lead to a transgenic organism capable of producing lactic acid.Plan all necessary steps to produce this strain:Which yeast will you use? From where will you get it?LDH: From which organism, where/how will you get the gene?Vector: Which essential part must the vector contain? Where will you get it, buy, construct….?How can you clone the LDH gene into the vector? REN, cutting sites, primer….Which transformation method will you use?How will you screen for positive transformants? Isolation, master cell bank…How will you prove the correct gene transfer and the production of lactic acid?The concept can/should be individual and in theory functional. There is no silver bullet (yeast strain, LDH gene, cloning, transfer, vector, detection…). Lively discussion between colleges is encouraged. Identical or recycled concepts from previous year will not be tolerated!At the end the concept will be presented to your colleges in the frame of a short presentation. Length of the written presentation: 4 Pages.
Graded will be the writen concept and the presentation.
Independent preparation of the concept and the presentationLectures:22.8: Preliminary discussion: Goal of the seminar and recapitulation of importance methods25.9: First Meeting: Q&A, crude concept should already exist10. or 13.10: Second Meeting: one on one discussion, 15 minutes per person to discuss final questions20.11: Presentation
Lector: Dr. Christian Leitner, Dr. Matthias Steiger
Construction of an expression vector to produce l-lactic acid in Saccharomyces cerevisiae1.) Isolation of the l-lactat-dehydrogenase gen form Lactobacillus plantarum2.) Construction and amplification of the expression vector in E. coli3.) Transferring the expression vector in the target organism S. cerevisiae and measurement of the LDH activity
Writing a scientific lab protocolRecommended language: German or English Rated will be the protocol and the practical work in the lab.
After a theoretical introduction at the beginning of each lab day the students will conduct the experiments by themselves with help from the protocols.
Lector: Dr. Christian Leitner, Dr. Nico Lingg, FH-Prof. DI Dr. Michael Maurer, Katharina Seiberl, Dr. Matthias Steiger
The course consists of two parts:1.Brewing technology2.Characterization of a recombinant yeast strainIn the course of the brewing technology, beer, liquor and vinegar are produced. This includes the process design, QA, filling and labeling.In the second part, a yeast strain producing lactic acid (outcome of the molecular biological lab) will be characterized in terms of productivity in comparison to the wild type and a mutant strain (PDC neg.)
Lector: Dipl.Ing. Dr. Christine Prenner, Prof. Dr. Karola Vorauer-Uhl
This course is aiming two major goals:First of all to develope a common understanding in quality-control-systems conserning the differences to general analytics. Secondly, to deepen the knowledge and background of methods applied in breweries.
Homework, presentation and discussion: 30%Final, written examination: 70%
This course has been established as an interactive workshop:Therefore, each student has to prepare a PowerPoint presentation, which has be presented in course.Based on this presentation, methodological- and quality related aspects will be discussed. The reguired documents for the individual homework are presented on the moodle-plattform. The presentations need to be uploaded prior the presentation. The presentation time is restricted to 10 min.
Case studies from the following subject areas:Acceptance sampling for attributes and variables in food production, confidence intervals and tests, Monte Carlo simulations, statistical process control, analysis of experiments, inter laboratory tests.
Presentation and written report.
Short inputs about the topic of the projects (background, statistical methods, R-specifics). Statistical consulting during the working out of the project.
Lector: DIin Sarah Kerschbaum, Dipl.-Ing. Dr. Sylvia Weilner
Dunzinger1. Isolation of cells2. Hayflicklimit, telomeres and telomerase3. Specialised cells4. Immortalisation of cell lines5. Tissue engineering, OrgankulturFliedl1. Cell culture laboratories, steril technique and cryoconservation2. Cultivation methods, cell number, media and components3. Cell line characterisation4. Application of animal cell lines and development of recombinant cell lines
Basic concepts of bioinformatics will be discussed and practices.- Working with Sequences as data type- phylogenetic trees- hidden markov models
practical programming task
lecture (powerpoint)practical work using computers
Lector: Dr. Matthias Gerstl
- Data types- R scripts- Control structures- Functions- Packages- Plots
Project work with final oral exam
Lecture and Exercise
Lector: DI Norbert Auer, Anna Tomaselli, BSc
This course is the first course for a student planning to study computer programming. The course content introduces the student mainly to both procedure-oriented and with basics on object-oriented programming languages. Structured programs will be written with a computer programming language (Python 3) with an emphasis on procedure-oriented programming. Topics will include basic computer hardware architecture constructs, flowcharting, pseudocode, top down design, logic structures, data structures and types, decisions, subroutines, looping, sequential file processing, data collection types and building basic graphical user interfaces.
The final exam will consists of 2 parts:1. A multi-choice test on all the arguments covered during the lectures2. A small programming exercise on the PC
The course will consist of frontal lectures and in-classroom programming on PC using Python 3 as programming language.
Lector: Univ.-Prof. Dipl.-Ing. Dr. techn. Christoph Herwig, Markus Pichler, MSc
Process equipment for upstream, recovery and downstream process, as well as for process supply and central utilitiesPiping, armatures and valvesBuilding concept / plant layout / hygiene conceptCleaning and sterilizationAutomationPlanning processQualification
- Presence in the lecture- Written final test (positive grading in case of > 60% of possible points)- Oral examination in case of negative test result- Unexcused absences (> 20%) or unexcused no-show to examination equivalent to a negative test result
Lecture with power point presentation
The course will be held in German - see German description
Continuous assessment, course work
Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, FH-Prof. DI Dr. Michael Maurer
see german description
See german description
Lector: Dipl.-Ing. Daniel Burgstaller, Dr. Nico Lingg
The recombinant proteins produced in the fermentation laboratory course will be purified with typical unit operation. The course covers homogenization, centrifugation, chromatography and ultra-/diafiltration.
- Colloquium- Protocol- Participation
Pactical course in groups
Lector: DI(FH) Robert Schwarz
The course addresses the technology of manufacturing aseptically prepared liquida and methodes to assess the process performance.
Written Exam and participation during lectures
The completion of an internship is part of the course of studies.
Further information: see portal downloads (only accessible for students, other people interested can inquire information in the office of the study program)
Good Manufacturing Practice (GMP) forms a quality framework for the production of pharmaceutical and biotechnological products. Plant Hygiene represents a central pillar of GMP, both in the way of general principles for avoiding adventious product contamination and through specific forms of implementation and instruments.
lectured course and participation
Lector: Florian Bacher, MSc.
Downstream processing means the treatment or purification of fermentation products. The lecture explains procedural basic operations as well as the purification and separation processes of metabolites.Emphasis is placed on mechanical and thermal separation processes, their application areas and their use on the industrial scale.On the basis of the general methods, special cleaning steps are also shown.
Lecture and discussion
Lector: Dipl.-Ing. Dr. Astrid Dürauer
Basics about downstream processing of proteins including impact factors and quality requirementsBasics about important methods e.g. centrifugation, filtrationt, cell disruption, precipitation, chromatographyCalculations of processes
written exam incl. calculation
Lector: FH-Prof. DI Dr. Michael Maurer, Mag. Dipl.-Ing. Dr. Martin Pfeffer, Mag. Karin Pfeffer, Katharina Seiberl
The aim of this course is the design, operation and analysis of a controlled bioprocess. Therefore, the recombinant E. coli strain will be cultivated in a batch fermentation.
- colloquium- report- active participation
Mentoring during the professional practical training
Lector: DI (FH) Anton Grünberg, Ing. DI (FH) Nadine Elpida Tatto
Lecture part about system softwares:The operating system Linux is essential in bioinformatics. This lecture and exercise provides an introduction to Linux in general and the usage of the operating system in particularData base systems:- Theory:In this part we will learn the basics of relational data base systems and SQL.- Training:The training will take place in small groups. The purpose of the training session will be to set up a small use case with MySQL.
Lecture part about system softwares:written exam and complete and punctual delivery of exercises. The grade will be calculated from exam and excercises 70%/30%.Data base systems:Written exam. The grade will be calculated from exam and excercises 70%/30%.
Lecture part about system softwares:Lecture and exercises during lecture time and at homeData base systems:Lecture and exercises during lecture time and at home
Lector: DI Norbert Auer, Dr. Matthias Gerstl, FH-Prof.in Mag.a Dr.in Alexandra Graf, Anna Tomaselli, BSc
Based on the programming lectures so far, this lecture finalizes important programming concepts with Python. Practical examples from different areas, such as functions, class hierarchies, polymorphism, interfaces, exceptions, modules, and file in/output, are presented and practiced.
This lecture is the basis for the bachelor thesis and will be appraised together with it.
Presentation and dialogs,interactive work and studies,practice on our notbooks
Semester datesSummer semester: 5th February 2018 to 14th July 2018Winter semester: 20th August 2018 to 26th January 2019
Number of teaching weeks20 per Semester
Times6.00 p.m.-9.20 p.m. (ca. three times from Mon to Fri)Sat, ca. every 2 weeks from 8.30 a.m. (allday)
Language of instructionGerman
Your will receive an education for a growth market. Biotechnology is a key technology of the 21st century that is booming internationally as well as in Austria. Right here in Vienna, a dynamic life science cluster has developed that has also created many jobs in the industry. You will be qualified for a wide range of fields from traditional biotech companies that manufacture pharmaceuticals, to various industries in which bioengineering methods are used in the production of foods, industrial chemicals, other biotechnology products or in brewing and beverage production.
With your expertise as a bioengineer you will work primarily on optimizing and further developing biotechnological production processes and methods that already work in the lab so that they are also suitable for the commercially viable production in the industry. Quality control and quality assurance play an important role in the production. In the medium term, you will be able to head the production, laboratory or project management.
Equivalence is determined by international agreements, validation or in individual cases a decision by the head of the academic section.
For more information about which university entrance qualification examinations are recognized, please visit the secretary's office.
Chemistry lab technology, chemical process technology, pharmaceutical technology, brewing and fermentation technology, food technology. Further information about the auxiliary examinations is available at the Secretary's office.
There are 40 places available in the bachelor's degree program in Bioengineering each year. The ratio of places to applicants is currently around 1:1,5.
To apply you will require the following documents:
Certificates from abroad as well as a description of the courses and exemplary documents from the applicant must be submitted as certified translations. Letters of recommendation from teachers from the institute abroad will help the head of the academic section to assess whether the admission requirements have been fulfilled.
Please note:It is not possible to save incomplete online applications. You must complete your application in one session. Your application will be valid as soon as you upload all of the required documents and certificates. In the event that some documents (e.g. references) are not available at the time you apply, you may submit these later via email, mail or in person by no later than the start of the degree program.
The selection process consists of a written test and an interview with the selection committee.
The study places are awarded at the latest in mid-July based on this ranking. The process as a whole and all test and assessment results from the selection process are documented in a transparent and verifiable manner.
Academic Staff T: +43 1 606 68 77-3600 email@example.com
Forschung und Entwicklung
Head of Section
We work closely with numerous industrial companies, universities such as the University of Natural Resources and Life Sciences, Vienna (BOKU) and the associated Vienna Institute of Biotechnology (VIBT) and other research institutes. This guarantees you strong contacts for internships, employment or participation in research and development activities. You can find information about our cooperation activities and much more at Campusnetzwerk. It’s well worth visiting the site as it may direct you to a new job or interesting event held by our cooperation partners!