Bioprocess Technology

Master, part-time

Overview

The unique characteristics of the living cell are what make the process technologies different from others. Bioprocess technology makes it possible to transfer biotechnological methods to technical applications in the industry. Procedures that are already established in the laboratory must be optimized so that they work well for industrial production on a large scale. In addition to process technology know-how, this also requires knowledge about biotechnology, biopharmaceutical technology and laboratory practice. Quality management and quality assurance provide important parameters.

Contact us

Contact us!

Elisabeth Beck
Elisabeth Holzmann, Bakk.techn.
Johanna Bauer
Barbara Philipp
Muthgasse 62
1190 Vienna
T: +43 1 606 68 77-3600
F: +43 1 606 68 77-3609
bioengineering@fh-campuswien.ac.at

Office hours during semester
Mon. to Thu. 4:30 p.m. to 6:00 p.m.

By appointment
Mon. to Thu. 10:00 a.m. to 6:00 p.m.
Fri. 10:00 a.m. to 1:00 p.m.

Stay up to date

Stay up to date!

Duration of course
4 Semester
Final degree
Master of Science in Engineering (MSc)
18Study places
120ECTS
Organisational form
part-time

Application period for academic year 2019/20

1st January 2019 to 30th June 2019

tuition fee / semester:

€ 363,36*

+ ÖH premium + contribution**

 

* Tuition fees for students from third countries € 727 per semester

 

**for additional study expenses
(currently up to €83 depending on degree program and year)

What you can offer

You have basic know-how in process technology and natural sciences. You are a process-oriented, system-related and analytical thinker. Innovation excites you. You want to strengthen your research skills in order to further develop and optimize process technologies. You enjoy working on projects in a team and would like to take on management responsibilities. Average English skills are expected. Language of instruction is German

What we offer you

Your education and research benefit from our close partnerships with well-known biotech companies as well as the University of Natural Resources and Life Sciences, Vienna (BOKU) and the Vienna Institute of Biotechnology (VIBT), who share the campus with us. The partnership enables you to take advantage of the BOKU's excellent infrastructure. In addition to the laboratories, this includes an industrial pilot plant with which it is possible in a preliminary stage to research production processes on a laboratory scale. Furthermore, numerous R&D projects in the degree program offer you the opportunity to work with cutting-edge applications and to make valuable contacts for your future career. Practical relevance is also guaranteed at our Campus Lecture evenings, which are open to all and feature contributions from prominent experts.

Bioprocess technology makes it possible to transfer biotechnological methods to technical applications in the industry. Microorganisms, animal cells or other biological materials can be used in a variety of technical applications to produce individual products, to develop test kits or to plan production plants. A bio-industrial pilot plant at our campus provides us the unique opportunity of being able to develop biotechnological production processes on a laboratory scale and transfer them to the pilot scale in order to precisely research their scalability.

The simulation of the production processes on a pilot scale helps determine deviations in each process step and develop process parameters for the commercial evaluation of the production processes. The results benefit teaching, research and the industry. For example, we use the facility together with the multi-technology company 3M to evaluate the latest filtration systems and applications for the production of medicinal products.

What makes this degree program special

Bioprocess technology makes it possible to transfer biotechnological methods to technical applications in the industry. Microorganisms, animal cells or other biological materials can be used in a variety of technical applications to produce individual products, to develop test kits or to plan production plants. A bio-industrial pilot plant at our campus provides us the unique opportunity of being able to develop biotechnological production processes on a laboratory scale and transfer them to the pilot scale in order to precisely research their scalability.

The simulation of the production processes on a pilot scale helps determine deviations in each process step and develop process parameters for the commercial evaluation of the production processes. The results benefit teaching, research and the industry. For example, we use the facility together with the multi-technology company 3M to evaluate the latest filtration systems and applications for the production of medicinal products.


What you will learn in the degree program

The degree program focuses on process technology, biotechnology, biopharmaceutical technology and practical laboratory experience.

  • Process technology covers control technology and plant engineering as well as plant design. In biotechnology you will specialize in bioprocess technology, downstream processing including practical laboratory experience, industrial microbiology and waste management technologies.
  • Within the framework of biopharmaceutical technology you will acquire knowledge about pharmacology, toxicology, company hygiene, process analysis, quality control and validation.
  • Knowledge of patent law, project management and corporate management will round out your portfolio. You will apply the methods of scientific work within the framework of your master's thesis.

Curriculum

Lecture SWS ECTS
Automation Tutorial LB

Automation Tutorial LB

Lector: Dipl.-Ing. Werner Seiler

1 SWS
2 ECTS

Lecture contents

Construction of various simple control circuits and comparison of different control strategies.
Each student builds her own control circuit using an Arduino starter kit, puts them into operation and studies their behaviour.

Assessment methods

Participation and protocol, final discussion.

Teaching methods

Experiments with an Arduino starter kit and a laptop.

Language

German

1 2
Biogas Production and Algal Technology VO

Biogas Production and Algal Technology VO

Lector: Dr. Katharina Meixner, Dipl.-Ing. Dr. Lydia Rachbauer

1 SWS
2 ECTS

Lecture contents

Overview on the biogas technology for energy recovery from renewable resources in combination with Algae technology for the develepment of biorefinery concepts.
A focus will be put on process regulation and application fields for both technologies.


Understanding of the specific conditions of providing energy from renewable resources and the pros and cons of these technologies, Communication of technological and microbiological basics of biogas and bioethanol technologyOverview

Assessment methods

written exam

Teaching methods

presentations

Language

German

1 2
Bioreactors and Bioprocess Engineering ILV

Bioreactors and Bioprocess Engineering ILV

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, FH-Prof. DI Dr. Michael Maurer

2 SWS
4 ECTS

Lecture contents

After the introduction, where the basic concepts and principles of bioprocess engineering are explained, the main bioreactor types and operation modes are presented. In the following section the kinetics of bioprocesses together with the underlying equations and graphs are outlined. Heat and mass transfer correlations, which are essential to be familiar with - especially for the design of bioreactors, are dealt in the following section. The characterization of various bioreactor types including enzyme reactors as weell as the upscaling principles are main topics of this lecture. Finally the basics of the sterilization technology and the design of SIP procedures are elucidated.
The understanding as well as the benefit of the presented model equations for the particular unit operations are shown by some selected examples.

Assessment methods

Two written intermediate exams and a final test.

Teaching methods

The teaching is based on the following concept:
First the scientific principles involved in a specific unit operation within biochemical engineering together with their practical application are elucidated. After a thorough discussion on the limitations of the respective Mathematical Model its practical value is shown by some examples.

2 4
Bioprocesses and Products VO

Bioprocesses and Products VO

Lector: Dr. MMag. Agnes Bugajska-Schretter, Dipl.-Ing. Helga Sgardelli, Dr. Martin Spruth

1.5 SWS
3 ECTS

Lecture contents

This course will introduce biological and biotechnological manufactured products with the focus on medicinal products (blood products, vaccines, recobinant proteins, biosimilars). Basic knowledge on technological processes and manufacturing methods as well as on genetics, immunology and history of biotechnology will be summarized.
Practical approaches for utilization of the products and for working in the biotech environment will be highlighted (key player in the biotech industry, vaccination programs, biotech company, license).

Assessment methods

final exam

Teaching methods

Lecture

1.5 3
Differential Equations for Bioprocess Engineering ILV

Differential Equations for Bioprocess Engineering ILV

Lector: Dipl.-Ing. Dr.mont. Paul Surer

1 SWS
2 ECTS

Lecture contents

1. Part
basic concepts of differential and integral calculus
solution of differential equation
linear differential equations
2.Part
Tutorial

Assessment methods

participation, exercises

Teaching methods

lecture

1 2
Energy, Heating and Cooling Technologies I ILV

Energy, Heating and Cooling Technologies I ILV

Lector: Ao.Univ.Prof. Dipl-Ing. Dr. Senad Novalin

1.5 SWS
3 ECTS

Lecture contents

1 Thermodynamics
1.1Introduction
1.2Change in State
1.3The First Law of Thermodynamics
1.4 Thermal calculations
1.5 The Second Law of Thermodynamics
1.6Work - Fluid Systems
1.7 Exergy
1.8 Heat Transfer
2 Technical Heat Transfer

Assessment methods

Written examination

Teaching methods

Lecture

1.5 3
Measurement, Control and Automation ILV

Measurement, Control and Automation ILV

Lector: Prof. Dr.-Ing. Richard Biener, Maria Schrammel, BSc

1.5 SWS
3 ECTS

Lecture contents

introduction to control theory
Controllers (PID-control, two-position control, cascade control,…)
requirement to control loops (performance, stability)
control design, determination of controller paameters
control of bioreactors (temperature, pH, pO2)
practical design of flow and level control

Assessment methods

written exam

Teaching methods

lecture
exercises
practical training

Language

German

1.5 3
Parenterals VO

Parenterals VO

Lector: O.Univ.-Prof. Mag.pharm. Dr. Helmut Viernstein

1 SWS
2 ECTS

Lecture contents

The course addresses the technology of manufacturing formulations for the parenteral application as well as methods of quality control according to the rules of the European and international pharmacopeia. In this context, well established formulations and innovative products will be presented and special biopharmacutical aspects will be discussed.

Assessment methods

written examination

Teaching methods

lecture

Language

German

1 2
Platform Chemicals and Biopolymeres ILV

Platform Chemicals and Biopolymeres ILV

Lector: DI Dr. Hans Marx

1.5 SWS
3 ECTS

Lecture contents

Terminology; overview regarding the market situation
- Biotechnological processes for the production of biobased materials and/or their monomeric precursors:
Feedstocks for fermentation and their availability;
Chemical derivatisation/synthesis of bioplastics; processing and moulding (especially thermoplastic moulding, e.g. extrusion and injection moulding); examples for applied moulding processes

Assessment methods

written examination

Teaching methods

lecture and practice

Language

German

1.5 3
Technical Risk Analysis ILV

Technical Risk Analysis ILV

Lector: Dr. Reinhard Preiss

1 SWS
2 ECTS

Lecture contents

Basic considerations in Risk Management
Terminology in the field of risk analysis;
Typical fields of application and legal aspects;
Process safety incidents;
Risk assessment (qualitativ, quantitive, semi-quantitative);
Analysis methodologies:
FMEA
HAZOP
Fault Tree Analysis (Basics)

Assessment methods

written exam

Teaching methods

Presentation, common acquirement of working examples.

Language

German

1 2
Validation ILV

Validation ILV

Lector: DI(FH) Robert Schwarz, Brigitta Schwarz

2 SWS
4 ECTS

Lecture contents

The course covers the foundation of validation, regulatory requirements and guidelines, equipment qualification (DQ, IQ, OQ, PQ), risk analysis, method validation, process validation, cleaning validation and sterilization/sanitization validation. Focusing of the preparation of associated documentation through validation projects will be included in practical detail.

Assessment methods

Concurrent performance assessment for active participation and permanent review to content already bespoken incl. solving examples to demonstrate the ability to apply the content practically.
If at the end of the last lesson before the written test less than 60 % of the required performance were provided in addition, following the written test an oral examination has to be undergone. This will be communicated the students affected in an appropriate manner (in person, by mail).
Written Exam (multiple choice, text questions and sample calculations)

Weighting of the final grade:
Written Exam 50%, active participation 20% and documents 30% (each part must be completed with a positive grade)

Teaching methods

Lecture, discussions and examples
The lecture slides and additionally the comments of the lecturer during the lecture are the basis of the course content.
The sum of this all is relevant for the permanent review and the written test.

Language

German-English

2 4

Lecture SWS ECTS
Plant Cleaning ILV 1 2
Selected Subjects in Bioprocess Engineering and Master Thesis Preparation SE 1 2
Downstream Processing (Practical Course) LB 3 6
Downstream Processing, Proteins ILV 1.5 3
Energy, Heating and Cooling Technologies II ILV 1.5 3
Enzyme Technology VO 1 2
Bioprocess Engineering (Practical Course) LB 2 4
Pharmaceutical Technology ILV 2 4
Specific Statistics ILV 1 2
Statistical Design of Experiments I ILV 1 2

Lecture SWS ECTS
Wastewater Treatment ILV

Wastewater Treatment ILV

Lector: Mag. Dr. Andreas Franz, Maria Schrammel, BSc

1.5 SWS
3 ECTS

Lecture contents

This course is held in German. The description is therefore also restricted to German.

Assessment methods

This course is held in German. The description is therefore also restricted to German.

Teaching methods

This course is held in German. The description is therefore also restricted to German.

Language

German

1.5 3
Plant Design and Construction ILV

Plant Design and Construction ILV

Lector: DI Josef Kriegl

1 SWS
2 ECTS

Lecture contents

Plant Engineering: Phases of Engineering and Construction of facilities. Explanation of enginering issues and engineering steps. Arrangement of equipments, utilities and site function for ideal material and personal flows, by taking the cleanroom classifications unter consiteration. Dimensioning of rooms sizes and definition of quality standards of rooms. Listing of necessary site functions for utilities.
Mechanical Process Design: Basic needs and quality standards for equipments, pipes, valves and instruments (design, form, materials)

Assessment methods

written examination after the course

Teaching methods

Lecture

Language

German

1 2
Industrial Facility Hygiene VO

Industrial Facility Hygiene VO

Lector: DI(FH) Robert Schwarz

1 SWS
2 ECTS

Lecture contents

Good Manufacturing Practice (GMP) forms a quality framework for the production of pharmaceutical and biotechnological products. Plant Hygiene represents a central pillar of GMP, both in the way of general principles for avoiding adventious product contamination and through specific forms of implementation and instruments.

Assessment methods

Written Exam and participation during lectures

Teaching methods

lectured course and participation

Language

German-English

1 2
Biosafety and Biosecurity VO

Biosafety and Biosecurity VO

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem, Mag. Dr. Andreas Franz

1 SWS
2 ECTS

Lecture contents

This course willl convey concepts and requirements for biological safety, as well as occupational health and safety, as covered in EN 45000.
In this context the course will include a discussion of biological risk, followed by related and required measures measures as defined by the risk classes and the austrian VbA.

Assessment methods

Final Exam

Teaching methods

Lectured Course

Language

German-English

1 2
Business Plan and Cost Accounting ILV

Business Plan and Cost Accounting ILV

Lector: Mag. Dipl.-Ing. Dr. Martin Pfeffer, Mag. Karin Pfeffer

2 SWS
4 ECTS

Lecture contents

"hands-on" priciples in business administration
Development of a business plan

Assessment methods

preparation & presentation of a business plan

Teaching methods

lecture, Workshop

Language

German

2 4
Fermentation Practical LB

Fermentation Practical LB

Lector: Ing. Michael Geissler, MSc., FH-Prof. DI Dr. Michael Maurer, Maria Schrammel, BSc

1 SWS
2 ECTS

Lecture contents

Brewing at a Craft Beer Brewery:
> Recipe design
> Scale up 50L -> 10hL and comparison
> QA/QC of brewing process
> Filling - KEGs and bottles
> Marketing

Assessment methods

Protocol

Teaching methods

practical course

1 2
Innovation and Entrepreneurship ILV

Innovation and Entrepreneurship ILV

Lector: Dipl.-Ing. Dr. Gottfried Himmler

1 SWS
2 ECTS

Lecture contents

The Entrepreneur

How do new things develop?
Recipies for success?

What is an enterprise?
Systems theory perspective

What is management?
Entrepreneur versus Manager:
Tasks
Character

The idea
The Business Model
The Business Plan

The ideal Leader.
Basics of Management.
Tasks of Managers.
Management Tools.

Assessment methods

Oral

Teaching methods

Lecture & Workshop

Language

German

1 2
Microbial Production Strains and Strain Development VO

Microbial Production Strains and Strain Development VO

Lector: FH-Prof. DI Dr. Michael Maurer, Dr.rer.nat. Christoph Metzner

1.5 SWS
2 ECTS

Lecture contents

Short introduction: Products, expression systems, markets
Metabolic Engineering: Aims, Prerequisites, Methods
Optimising Product or Production?
Focus Biomedicine: Antibody – Vaccine - Gene therapy vector
Examples from recent publications
Bottlenecks in Production/Upscaling
Mini seminar on Metabolic Engineering on a real-life example: „ Glycosylphosphatidylinositol-Protein Production for VLP vaccines – Assessing different strategies“

Assessment methods

Final Exam

Teaching methods

Lecture - e-learning - mini-seminar - discussion

Language

German-English

1.5 2
Molecular Biology Laboratory Practical LB

Molecular Biology Laboratory Practical LB

Lector: Dr. Johannes Pichler, Maria Schrammel, BSc

1 SWS
2 ECTS

Lecture contents

Introduction to eukaryotic (mammalian) cell culture
Basic Methods: Thawing, Splitting, Seeding, Harvesting, Freezing,
Transfection methods: Co-precipitation and lipofection
Influence of e.g. different plasmid backbones or different host cell lines on product
Analysis: Fluorometric, cytotoxicity, protein content (specific vs. total)

Assessment methods

Continuous assessment of course work/protocol

Teaching methods

Lecture, experimentation, discussion

Language

German-English

1 2
Patenting ILV

Patenting ILV

Lector: Dipl.-Ing. Anatol Dietl, Mag. iur. Dipl.-Ing. Dr. Michael Stadler

1 SWS
2 ECTS

Lecture contents

Protective rights; Reading patent documents; scope of protection; novelty, state of the art; inventive step; further requirements of patentability; patent application procedure; international patent laws and treatys; patent licensing;

Assessment methods

written tests at the beginning of the lecture units; homework problem

Teaching methods

Lecture

Language

German

1 2
Statistical Design of Experiments II UE

Statistical Design of Experiments II UE

Lector: Dr. Reinhard Ilk

1 SWS
2 ECTS

Lecture contents

Structure of statistical designs for more than two factors, differences between individual designs with regard to extent, output and results of various experimental designs. Analysis of experiments by using t-statistics and the General Linear Model (GLM).

Assessment methods

Test mode:
Exercises to be performed within the lecture sequence. Written test after lecture is finished. The test will consist of a combination of multiple-choice questions and application examples with open questions. Working with the software will be part of the exercises, but not part of the test!
The grading is based to each one-third on the performance of the exercise and the two parts of the written test. Attendance and contribution is recognized whenever the evaluation decision is marginal. In case the test is failed, the repeat test will always be held as an oral exam.

Teaching methods

Lecture with embedded practical exercises. The content will be taught in training locations enabling access to statistics software provided. Work on exercise examples can be done on individual time management.

1 2
Sterilization and Disinfection ILV

Sterilization and Disinfection ILV

Lector: Hon.-Prof. Univ.-Doz. DI Dr. Rudolf Friedrich Bliem

1 SWS
2 ECTS

Lecture contents

Terms and overview of processes for microbial inactivation
Processes of moist heat inactivation, as well as chemical and thermal disinfection
Predictive calculation models

Assessment methods

written exam

Teaching methods

Lectured course

Language

German-English

1 2
Technical Project Management ILV

Technical Project Management ILV

Lector: DI Josef Kriegl

0.5 SWS
1 ECTS

Lecture contents

In addition to the different tasks involved in the project management of biotechnological plants, which include process engineering as well as supply engineering and buildings, topics such as fast track, sustainability or risk prevention are decisive factors for the success of projects.

Assessment methods

written exam

Teaching methods

Lecture

0.5 1
Water and Ventilation Technology ILV

Water and Ventilation Technology ILV

Lector: Ing. Walter Lintner, Ing. Otmar Pribitzer

1 SWS
2 ECTS

Lecture contents

Water, Potable Water, Purified Water, Methodes of Purification, Maintenance, Equipment for mesuring parameters

Assessment methods

graduation work

Teaching methods

lecture with slides, lecture notes

1 2

Lecture SWS ECTS
Master Thesis Supervision MP 0 1
Master Thesis MT 0 28
Master Thesis Seminar SE 1 1

Semester dates
Summer semester 2019: 11th February to 12th July 2019
Winter semester 2019/20: 19th August 2019 to 1st February 2020

Number of teaching weeks20 per semester

 

 

Times
6:00 p.m. to 9:20 p.m. (ca. three times from Mon to Fri), Sat ca every two weeks from 8:30 a.m. (all day)

Language of instruction
German


Career opportunities

Bioprocess technology experts with a strong basis in GMP (Good Manufacturing Practice) and GLP (Good Laboratory Practice) are particularly sought after. Your professional spectrum will extend from the planning, development and implementation of biotechnological production processes all the way to the operation of biotechnological plants. You will find a career in the following occupational fields:

  • Biopharmaceutical industry
  • Industrial biotechnology
  • Food industry
  • Environmental technology
  • Plant engineering

Admission

Admission requirements

  • Bachelor degree in natural sciences-technology or similar qualification from an institute of higher education with a total of 180 ECTS credits

With at least
> 60 ECTS credits in natural sciences (chemistry, microbiology, mathematics, statistics, biochemistry, molecular biology) and
> 13 ECTS credits in technical subjects (process engineering, principals of bioprocess technology, measurement and control technology).
More information is available upon request.

Equivalence is determined by international agreements, validation or in individual cases a decision by the head of the academic section.

Application

There are 18 places available in the master’s degree program in Bioprocess Technology each year. The ratio of places to applicants is currently around 1:1,5.

To apply you will require the following documents:

  • Bachelor/diploma certificate or equivalent certificate from abroad

Certificates from abroad as well as a description of the courses and exemplary documents must be submitted as certified translations.Letters of recommendation from teachers from the institute abroad will help the head of the academic section to assess whether the admission requirements have been fulfilled.

  • List of courses completed or transcript
  • Letter of motivation
  • CV in table form

Please note:

It is not possible to save incomplete online applications. You must complete your application in one session. Your application will be valid as soon as you upload all of the required documents and certificates. In the event that some documents (e.g. references) are not available at the time you apply, you may submit these later via email, mail or in person by no later than the start of the degree program.

The selection process

The selection process consists of a written test and an interview with the selection committee.

  • Aim
    The aim is to ensure places are offered to those persons who complete the multi-level selection process with the best results. The tests are designed to assess the skills needed for an applicant's chosen profession.
  • Procedure
    The written selection test assesses the applicant's knowledge of natural sciences and technology. Applicants then undergo a selection interview on the same day to provide a first impression of their personal aptitude. The qualities interviewers are looking for include professional motivation, an understanding of the profession, performance, time management. Points are assigned to each section of the test.
  • Criteria
    The criteria for acceptance are based solely on performance. The geographical origin of the applicant has no influence on the selection decision. The admission requirements must be met in all cases. Applicants are evaluated according to the following weighting system:
    > Written selection test (60%)
    > Selection interview (40%)

    The study places are awarded at the latest in mid-July based on this ranking. The process as a whole and all test and assessment results from the selection process are documented in a transparent and verifiable manner.

Contact

Secretary's office

Elisabeth Beck
Elisabeth Holzmann, Bakk.techn.
Johanna Bauer
Barbara Philipp
Muthgasse 62
1190 Vienna
T: +43 1 606 68 77-3600
F: +43 1 606 68 77-3609
bioengineering@fh-campuswien.ac.at

Office hours during semester
Mon. to Thu. 4:30 p.m. to 6:00 p.m.

By appointment
Mon. to Thu. 10:00 a.m. to 6:00 p.m.
Fri. 10:00 a.m. to 1:00 p.m.

Teaching staff and research staff


Cooperations and Campusnetzwerk

We work closely with numerous industrial companies, universities such as the University of Natural Resources and Life Sciences, Vienna (BOKU) and the associated Vienna Institute of Biotechnology (VIBT) and other research institutes. This guarantees you strong contacts for your professional career or participation in research and development activities. You can find information about our cooperation activities and much more at Campusnetzwerk. It's well worth visiting the site as it may direct you to a new job or interesting event held by our cooperation partners!

Campusnetzwerk