Signalling Pathways (Research Group) The working group “Signaling Pathways”, headed by Thomas Czerny, focuses the research questions of analysis and application of pathways. The measurement of pathway activities is essential for many applications. The research group specializes in measuring these activities as sensitively as possible. Cell-based test systems with luciferase-based reporter assays play an important role in achieving this. With this technology, for example, it was possible to establish highly sensitive assays for the detection of sensitizing chemicals (type-4 allergens). Currently, assays are being developed to detect inflammatory contaminants in medical devices and food packaging materials.